Results 31 to 40 of about 10,798,118 (310)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Trip Report on the Appalachian Adult Basic Education Special Project [PDF]

, 1969
A rough draft of the trip report on the Appalachian Adult Basic Education Special Project submitted by Appalachian Adult Basic Education Demonstration Center circa ...
Appalachian Adult Basic Education Demonstration Center
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The Identification and Comparison of Attitudes Toward Education by Adult Basic Education Students, Teachers, and Administrators [PDF]

, 1969
Final report on the Mississippi module of the Identification and Comparison of Attitudes Toward Education by Adult Basic Education Students, Teachers, and Administrators submitted in February of ...
Appalachian Adult Basic Education Demonstration Center
core  

Universal Basic Education (UBE) programme and school dropout syndrome in Northern States-Nigeria

Journal of Perspectives in Management
The study examined the effect of Universal Basic Education (UBE) Programme on school dropout syndrome in conflict-affected area Northern States Nigeria. This research used a descriptive survey research approach. The population of the study is made up of
Joseph Adekunle Bamidele, Oboromeni Weinoh, Abdul Rasheed Ahuoiza Aminat, Musa Zakari   +3 more
doaj   +1 more source

Comprehending the Cycle two of the Basic Education Learning Physical Education: Literature Review of the Physical Education Omani Curriculum [PDF]

Assiut Journal of Sport Science and Arts, 2018
This paperconsiders comprehending the cycle two student of the basic education learning physical education. General reviews will utilize the learners’ motivation and ability to reflect on the general Omani educational goal.
Yousra AL-Sinani
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Perception of Educators on Gender Equality: A Study in Ecuador

Social Sciences
Gender equality is a prerequisite for people-centered human development. This exploratory and descriptive study was conducted to investigate the perception of gender among Ecuadorian primary school teachers.
Verónica Díaz, Henry Vallejos, Carmen Oval, Selin Carrasco, Carmen Coloma, Fabiola Flores, Carola Lozada, Patricio Rivera, María Simón   +8 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Adult Basic Education Guidance and Counseling Workshop, June 22-26, 1970 [PDF]

, 1970
Final report on the Adult Basic Education Guidance and Counseling Workshop conducted from June 22 to June 26, 1970 and submitted by Appalachian Adult Basic Education Demonstration Center at Morehead State ...
Appalachian Adult Basic Education Demonstration Center
core