Results 261 to 270 of about 233,973 (306)

Basic fibroblast growth factor-induced seizures in rats

Neuroscience Letters, 1997
The neurotrophic effects of basic fibroblast growth factor on hippocampal neurons have been well documented. However, the acute effects of basic fibroblast growth factor on hippocampal electrical activities in vivo have not yet been studied. To assess the impact of basic fibroblast growth factor on hippocampal electroencephalographic (EEG) activity ...
Z, Liu, G L, Holmes
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Biotinylated basic fibroblast growth factor is biologically active

Analytical Biochemistry, 1991
Basic fibroblast growth factor (bFGF) was modified by biotinylation via amino group substitution, using biotin-N-hydroxysuccinimide ester at molar reaction ratios of 20, 200, and 2000 per bFGF molecule (respectively named bio-bFGF.20, bio-bFGF.200, and bio-bFGF.2000).
I, Pieri, D, Barritault
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BASIC FIBROBLAST GROWTH FACTOR IN HUMAN PITUITARY TUMOURS

Clinical Endocrinology, 1990
SUMMARYImmunoreactive (ir) basic fibroblast growth factor (FGF) has been measured in normal human pituitary glands and in 41 pituitary tumours of various types using a radioimmunoassay. Normal pituitary glands contained ir basic FGF ranging from 29.4 to 355 fmol/mg wet weight whereas 87.5% of pituitary tumours contained amounts of the growth factor ...
J J, Silverlight, R A, Prysor-Jones, J S, Jenkins   +2 more
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Cardioprotection and Basic Fibroblast Growth Factor

1996
Basic fibroblast growth factor (bFGF, or FGF-2) is a 18–25-kDa basic protein found in variable amounts in all tissues examined (see [1] for a recent review). It is highly conserved between species and belongs to a large family of FGF growth factors (FGF 1—9) with which it shares 40%–50% sequence homology; another widely studied member of this family is
Raymond R. Padua, Lei Liu, Rajat Sethi, Sarah E. Davey-Forgie, Naranjan S. Dhalla, Elissavet Kardami   +5 more
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Mast Cell Basic Fibroblast Growth Factor in Silicosis

American Journal of Respiratory and Critical Care Medicine, 2000
To investigate the role of mast cells (MC) and their fibrogenic growth factors in silicosis, we performed quantitative immunohistochemistry for MC tryptase and for basic fibroblast growth factor (bFGF) in lung tissue from silicotic and control subjects.
H, Hamada, V, Vallyathan, C D, Cool, E, Barker, Y, Inoue, L S, Newman   +5 more
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Basic Fibroblast Growth Factor and Angiogenesis

2006
Regenerative medicine using growth factors is an important therapeutic tool in patients with tissue ischemia or defects. Among such therapies, we have mainly addressed the sustained release of basic fibroblast growth factor (bFGF) as a safe and effective treatment.
Akira Marui, Kazuhiko Doi, Keiichi Tambara, Yutaka Sakakibara, Koji Ueyama, Atsushi Iwakura, Masaya Yamamoto, Tadashi Ikeda, Yasuhiko Tabata, Masashi Komeda   +9 more
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Monoclonal Antibodies Against Human Basic Fibroblast Growth Factor

Hybridoma, 1989
Recombinant human basic fibroblast growth factor (hbFGF) was used as an antigen to develop, by a somatic cell fusion technique, four monoclonal antibodies (MAbs), that recognize the complete and amino-terminal truncated form of hbFGF. Isotype identification showed that MAbs designated MAb12 and MAb98 were IgG1; and those designated MAb52 and MAb78 were
M, Seno, M, Iwane, R, Sasada, N, Moriya, T, Kurokawa, K, Igarashi   +5 more
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BASIC FIBROBLAST GROWTH FACTOR EXPRESSION IN PEYRONIE'S DISEASE

Journal of Urology, 2001
Peyronie's disease is a fibromatosis resulting in scarring of the tunica albuginea. While the inciting event is believed to be trauma to the erect penis, little is understood about the cascade of cellular events that leads to the formation of the plaque. Dysregulated wound healing serves as a paradigm for the study of this condition.
J P, Mulhall, J, Thom, T, Lubrano, T V, Shankey   +3 more
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Basic fibroblast growth factor positively regulates hematopoietic development

Development, 2000
ABSTRACT Recently identified BLast Colony Forming Cells (BL-CFCs) from in vitro differentiated embryonic stem (ES) cells represent the common progenitor of hematopoietic and endothelial cells, the hemangioblast. Access to this initial cell population committed to the hematopoietic lineage provides a unique opportunity to characterize ...
P, Faloon, E, Arentson, A, Kazarov, C X, Deng, C, Porcher, S, Orkin, K, Choi   +6 more
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Stabilizing basic fibroblast growth factor using protein engineering

Biochemical and Biophysical Research Communications, 1988
Using site directed mutagenesis, each of the four cysteines present at amino acid residues 26, 70, 88, and 93 of the mature protein of human basic fibroblast growth factor (bFGF) was individually changed to serine. The biological activity and heparin binding ability was retained when the serine was substituted for the cysteine residue at either 70 or ...
M, Seno, R, Sasada, M, Iwane, K, Sudo, T, Kurokawa, K, Ito, K, Igarashi   +6 more
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