Results 21 to 30 of about 233,973 (306)

Mechanism of fibroblast growth factor 21 in cardiac remodeling

open access: yesFrontiers in Cardiovascular Medicine, 2023
Cardiac remodeling is a basic pathological process that enables the progression of multiple cardiac diseases to heart failure. Fibroblast growth factor 21 is considered a regulator in maintaining energy homeostasis and shows a positive role in preventing
Zeyu Zhao, Xuemei Cui, Zhangping Liao
doaj   +1 more source

Presence and localization of a 30-kDa basic fibroblast growth factor-like protein in rodent testes [PDF]

open access: yes, 1991
We have used a recently characterized rabbit antiserum against basic fibroblast growth factor (bFGF), which recognizes various forms of bFGF, to examine the presence and localization of bFGF in the testes of adult rats and mice and the 5-day-old rat.
Gratzl, Manfred   +4 more
core   +1 more source

In situ formation of poly(vinyl alcohol)–heparin hydrogels for mild encapsulation and prolonged release of basic fibroblast growth factor and vascular endothelial growth factor

open access: yesJournal of Tissue Engineering, 2016
Heparin-based hydrogels are attractive for controlled growth factor delivery, due to the native ability of heparin to bind and stabilize growth factors.
Justine J Roberts   +4 more
doaj   +1 more source

Systematic optimization of human pluripotent stem cells media using Design of Experiments. [PDF]

open access: yes, 2015
Human pluripotent stem cells (hPSC) are used to study the early stages of human development in vitro and, increasingly due to somatic cell reprogramming, cellular and molecular mechanisms of disease.
Chailangkarn, Thanathom   +2 more
core   +1 more source

siRNA-mediated silencing of bFGF gene inhibits the proliferation, migration, and invasion of human pituitary adenoma cells

open access: yesTumor Biology, 2017
Human pituitary adenoma is one of the most common intracranial tumors with an incidence as high as 16.7%. Recent evidence has hinted a relationship between growth factors of pituitary or hypothalamic origin and proliferation of human pituitary adenoma ...
Kai Zhou   +6 more
doaj   +1 more source

Treatment of Skin Avulsion Injuries with Basic Fibroblast Growth Factor

open access: yesPlastic and Reconstructive Surgery, Global Open, 2015
Summary: This report describes favorable outcomes in 9 patients with skin avulsion injuries of the extremities who underwent full-thickness skin grafting and basic fibroblast growth factor (bFGF) application.
Hajime Matsumine, MD, PhD
doaj   +1 more source

Selective Desensitization of Growth Factor Signaling by Cell Adhesion to Fibronectin [PDF]

open access: yes, 2007
Cell adhesion to the extracellular matrix is required to execute growth factor (GF)-mediated cell behaviors, such as proliferation. A major underlying mechanism is that cell adhesion enhances GF-mediated intracellular signals, such as extracellular ...
Asthagiri, Anand R.   +3 more
core   +1 more source

Basic fibroblast growth factor enhances proliferation and hepatocyte growth factor expression of feline mesenchymal stem cells

open access: yesRegenerative Therapy, 2020
Introduction: The objective of this study is to evaluate the effect of basic fibroblast growth factor (bFGF) on the proliferation and secretion activity of feline adipose-derived mesenchymal stem cells (MSC).
Youhei Fujimoto   +3 more
doaj   +1 more source

Growth factors and experimental arterial grafts [PDF]

open access: yes, 2016
Background: The production of growth factors from several experimental arterial conduits was determined. Methods: We implanted 105 experimental arterial grafts that were 1 cm long in the abdominal aorta of Lewis rats (average weight, 250 g).
BORRELLI, Valeria   +6 more
core   +1 more source

Role of Basic Fibroblast Growth Factor in Cancer: Biological Activity, Targeted Therapies, and Prognostic Value

open access: yesCells, 2023
Cancer is the leading cause of death worldwide; thus, it is necessary to find successful strategies. Several growth factors, such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF, FGF2), and transforming growth factor ...
Alessio Ardizzone   +10 more
doaj   +1 more source

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