Results 141 to 150 of about 107,836 (184)

The mammalian basic helix-loop-helix/PAS family of transcriptional regulators.

The International Journal of Biochemistry & Cell Biology, 2004
Basic helix-loop-helix (bHLH)/PAS proteins are critical regulators of gene expression networks underlying many essential physiological and developmental processes. These include transcriptional responses to environmental pollutants and low oxygen tension, mediated by the aryl hydrocarbon (Dioxin) receptor and hypoxia inducible factors (HIF ...
R. Kewley, M. Whitelaw, A. Chapman-Smith
semanticscholar   +4 more sources

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene.

Cell, 1993
C. Yokoyama, Xiadong Wang, M. Briggs, A. Admon, Michael S. Brown   +4 more
semanticscholar   +5 more sources

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein.

Cell, 1993
C. Hodgkinson, K. J. Moore, A. Nakayama, E. Steingrímsson, N. Copeland, N. Jenkins, H. Arnheiter   +6 more
semanticscholar   +3 more sources

Mutations in TWIST, a basic helix–loop–helix transcription factor, in Saethre-Chotzen syndrome

Nature Genetics, 1997
T. Howard, W. Paznekas, E. Green, Lydia C. Chiang, Nancy Ma, R. O. D. Luna, Costanza Garcia Delgado, M. Gonzalez-Ramos, A. D. Kline, E. Jabs   +9 more
semanticscholar   +3 more sources

Calcium regulation of basic helix-loop-helix transcription factors

Cell Calcium, 1998
The basic helix-loop-helix (bHLH) family of transcription factors is essential for numerous developmental and growth control processes. The regulation of bHLH proteins occurs at many levels, including tissue specific expression, differential oligomerization and DNA binding specificities, interaction with negatively acting HLH proteins and post ...
S, Hermann, J, Saarikettu, J, Onions, K, Hughes, T, Grundström   +4 more
openaire   +2 more sources

Phylogenetic Analysis of Plant Basic Helix-Loop-Helix Proteins

Journal of Molecular Evolution, 2003
The basic helix-loop-helix (bHLH) family of proteins is a group of functionally diverse transcription factors found in both plants and animals. These proteins evolved early in eukaryotic cells before the split of animals and plants, but appear to function in 'plant-specific' or 'animal-specific' processes.
Michael J, Buck, William R, Atchley
openaire   +2 more sources

Phylogenetic Analysis of Zebrafish Basic Helix-Loop-Helix Transcription Factors

Journal of Molecular Evolution, 2009
The basic helix-loop-helix (bHLH) proteins play important regulatory roles in eukaryotic developmental processes including neurogenesis, myogenesis, hematopoiesis, sex determination, and gut development. Zebrafish is a good model organism for developmental biology.
Yong, Wang, Keping, Chen, Qin, Yao, Xiaodong, Zheng, Zhe, Yang   +4 more
openaire   +2 more sources

Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation

Development, 2000
ABSTRACT An intracellular timer in oligodendrocyte precursor cells is thought to help control the timing of their differentiation. We show here that the expression of the Hes5 and Mash1 genes, which encode neural-specific bHLH proteins, decrease and increase, respectively, in these cells with a time course expected if the proteins are ...
T, Kondo, M, Raff
openaire   +2 more sources

The role of basic helix-loop-helix genes in vertebrate retinogenesis

Seminars in Cell & Developmental Biology, 2001
The developing eye is a favorite model for the study of pattern formation and cell fate determination. Retinal neuron development, in particular, is an approachable system to study molecular and cellular aspects of cell determination and differentiation.
M L, Vetter, N L, Brown
openaire   +2 more sources

Basic helix‐loop‐helix transcription factor DEC1 negatively regulates cyclin D1

The Journal of Pathology, 2011
AbstractDEC1 (also known as Stra13/Bhlhb2/Sharp2) and DEC2 (also known as Bhlhb3/Sharp1) are two paralogous basic helix‐loop‐helix (bHLH) transcriptional regulators which exhibit a robust circadian gene expression pattern in the suprachiasmatic nucleus (SCN) and in peripheral organs.
Ujjal K, Bhawal, Fuyuki, Sato, Yuki, Arakawa, Katsumi, Fujimoto, Takeshi, Kawamoto, Keiji, Tanimoto, Yumi, Ito, Tomonori, Sasahira, Takashi, Sakurai, Masaru, Kobayashi, Isamu, Kashima, Hiroshi, Kijima, Hiroki, Kuniyasu, Yoshimitsu, Abiko, Yukio, Kato, Sadao, Sato   +15 more
openaire   +2 more sources