Results 151 to 160 of about 107,836 (184)

The basic helix-loop-helix transcription factor family in Bombyx mori

Development Genes and Evolution, 2007
The basic helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that play important roles in a wide range of developmental processes in higher organisms. bHLH family members have been identified in a dozen of organisms including fruit fly, mouse and human.
Yong, Wang, Keping, Chen, Qin, Yao, Wenbing, Wang, Zhu, Zhi   +4 more
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Phylogenetic analyses of vector mosquito basic helix‐loop‐helix transcription factors

Insect Molecular Biology, 2013
Abstract Basic helix‐loop‐helix ( bHLH ) transcription factors play critical roles in the regulation of a wide range of developmental processes in higher organisms and have been identified in more than 20 organisms. Mosquitoes are important vectors of certain human diseases.
D B, Zhang, Y, Wang, A K, Liu, X H, Wang, C W, Dang, Q, Yao, K P, Chen   +6 more
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The self-association of basic helix-loop-helix peptides

2008
As part of a study into the homo- and hetero-oligomerization properties of muscle-specific transcriptional factors, and their interation with DNA, sedimentation equilibrium studies, accompanied by circular dichroism measurements, have been made on peptides derived from the helix-loop-helix regions of MyoD and E47.
H. Wendt, R. M. Thomas
openaire   +1 more source

Calcium/calmodulin inhibition of basic-helix-loop-helix transcription factor domains

Nature, 1994
The ubiquitous Ca(2+)-binding protein calmodulin (CaM) is a key protein in Ca2+ homeostasis and activation of eukaryotic cells. CaM is the molecular link between free Ca2+ in the cell and the inhibition, or activation, of numerous enzymes. Many nuclear functions are under Ca2+/CaM control, and some transcriptional activators are known to be Ca2 ...
B, Corneliussen, M, Holm, Y, Waltersson, J, Onions, B, Hallberg, A, Thornell, T, Grundström   +6 more
openaire   +2 more sources

E2F1 inhibition of transcription activation by myogenic basic helix‐loop‐helix regulators

Journal of Cellular Biochemistry, 1996
Cellular transcription factor E2F1 is thought to regulate the expression of genes important for cell cycle progression and cell proliferation. Deregulated E2F1 expression induces S-phase entry in quiescent cells and inhibits myogenic differentiation. We show here that E2F1 inhibits the activation of gene transcription by myogenic basic helix-loop-helix
J, Wang, Q, Huang, W, Tang, B, Nadal-Ginard   +3 more
openaire   +2 more sources

Basic Helix–Loop–Helix Proteins Expressed During Early Embryonic Organogenesis

2004
The basic helix-loop-helix proteins form a special group of transcription factors unique for the eukaryotic organisms. They are crucial for the embryonic development of many fundamental organ systems such as muscle, heart, central nervous system, hematopoiteic system, and many others.
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Muscle basic helix-loop-helix proteins and the regulation of myogenesis

Current Opinion in Genetics & Development, 1992
Significant progress has been made in defining the structural motifs that distinguish the muscle-specific from other basic helix-loop-helix proteins. Evidence is accumulating for multiple levels of regulation of the expression and action of the muscle basic helix-loop-helix factors.
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Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein.

Science, 1995
Jacqueline E. Lee, Jacqueline E. Lee, S. Hollenberg, S. Hollenberg, L. Snider, L. Snider, D. Turner, Naomi Lipnick, Harold Weintraub, Harold Weintraub   +9 more
semanticscholar   +1 more source

em E2 em A basic helix-loop-helix transcription factors in human leukemia

Frontiers in Bioscience, 2003
The gene E2A on chromosome 19 is involved in recurrent chromosomal rearrangements associated with pediatric acute lymphoblastic leukemia. The resulting fusion of 5' E2A sequences with 3' portions of other genes leads to the expression of two well-characterized fusion proteins: E2A-PBX1 and E2A-HLF.
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The Basic Helix-Loop-Helix Transcription Factors in Neural Differentiation

2010
During the development of the central nervous system, neural stem cells initially expand their own population by symmetric cell divisions, in which both progeny re-enter the cell cycle. By mid-gestation, the cells initiate neurogenesis by adopting a mode of asymmetric cell division, in which one daughter cell differentiates into a neuron while the ...
Toshiyuki Ohtsuka, Ryoichiro Kageyama
openaire   +1 more source