The Evolution of the Neural Basic Helix-Loop-Helix Proteins
The Scientific World Journal, 2001 Basic Helix-Loop-Helix (bHLH) transcription factors control various aspects of the formation of the nervous system in the metazoans. In Drosophila some bHLH (such as the achaete-scuteatonal, and amos genes) act as proneural genes, directing ectodermal ...
Michel Vervoort, Valerie Ledent
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BMC Genomics, 2017 Background As a superfamily of transcription factors (TFs), the basic helix-loop-helix (bHLH) proteins have been characterized functionally in many plants with a vital role in the regulation of diverse biological processes including growth, development ...
Xin Niu +3 more
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Genome-wide analysis of the basic Helix-Loop-Helix (bHLH) transcription factor family in maize
BMC Plant Biology, 2018 Background In plants, the basic helix-loop-helix (bHLH) transcription factors play key roles in diverse biological processes. Genome-wide comprehensive and systematic analyses of bHLH proteins have been well conducted in Arabidopsis, rice, tomato and ...
Tingting Zhang +6 more
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Alternative Splicing of the Basic Helix–Loop–Helix Transcription Factor Gene CmbHLH2 Affects Anthocyanin Biosynthesis in Ray Florets of Chrysanthemum (Chrysanthemum morifolium) [PDF]
Frontiers in Plant Science, 2021 Chrysanthemum is an important ornamental crop worldwide. Some white-flowered chrysanthemum cultivars produce red ray florets under natural cultivation conditions, but little is known about how this occurs.
Sun-Hyung Lim +4 more
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Genome expression analysis of basic helix-loop-helix transcription factors in Sea buckthorn (Hippophae rhamnoides L.) [PDF]
Frontiers in Plant ScienceIntroductionThe basic helix-loop-helix (bHLH) transcription factor family is one of the largest gene families in plants, extensively involved in plant growth, organ development, and stress responses.
Jiajia Zhang +6 more
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Involvement of a Basic Helix-Loop-Helix Gene BHLHE40 in Specification of Chicken Retinal Pigment Epithelium [PDF]
Journal of Developmental Biology, 2022 The first event of differentiation and morphogenesis in the optic vesicle (OV) is specification of the neural retina (NR) and retinal pigment epithelium (RPE), separating the inner and outer layers of the optic cup, respectively.
Toshiki Kinuhata +6 more
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Genome-wide analysis of basic helix-loop-helix transcription factors in papaya (Carica papaya L.) [PDF]
PeerJ, 2020 The basic helix-loop-helix (bHLH) transcription factors (TFs) have been identified and functionally characterized in many plants. However, no comprehensive analysis of the bHLH family in papaya (Carica papaya L.) has been reported previously.
Min Yang +5 more
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eLife, 2018 The mesodermal germ layer is patterned into mediolateral subtypes by signaling factors including BMP and FGF. How these pathways are integrated to induce specific mediolateral cell fates is not well understood.
Richard H Row +7 more
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Homologous basic helix–loop–helix transcription factors induce distinct deformations of torsionally-stressed DNA: a potential transcription regulation mechanism [PDF]
QRB Discovery, 2022 Changing torsional restraints on DNA is essential for the regulation of transcription. Torsional stress, introduced by RNA polymerase, can propagate along chromatin facilitating topological transitions and modulating the specific binding of transcription
Johanna Hörberg +2 more
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Basic-helix-loop-helix family member e41 suppresses osteoclastogenesis and abnormal bone resorption disease via NFATc1 [PDF]
iScienceSummary: Overactivation of osteoclasts due to altered osteoclastogenesis causes multiple bone metabolic diseases. However, how osteoclast differentiation is tightly regulated and involved in multiple pathophysiological states remains mystery.
Yufeng Zhang +9 more
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