Results 51 to 60 of about 107,836 (184)

Basic helix‐loop‐helix protein MyoD displays modest DNA binding specificity

FEBS Letters, 1996
The expression of MyoD can activate muscle specific genes and myogenic differentiation in many cell types. The hypothesis that the DNA binding specificity of MyoD is responsible for its biological specificity was tested. Homodimers of MyoD bind to E‐box containing DNA with high affinity, but do not form stable and well defined complexes with ...
Künne, Andreas G.E., Meierhans, Daniel, Allemann, Rudolf K.   +2 more
openaire   +2 more sources

A Radish Basic Helix-Loop-Helix Transcription Factor, RsTT8 Acts a Positive Regulator for Anthocyanin Biosynthesis

Frontiers in Plant Science, 2017
The MYB-bHLH-WDR (MBW) complex activates anthocyanin biosynthesis through the transcriptional regulation. RsMYB1 has been identified as a key player in anthocyanin biosynthesis in red radish (Raphanus sativus L.), but its partner bHLH transcription ...
Sun-Hyung Lim, Da-Hye Kim, Jae K. Kim, Jong-Yeol Lee, Sun-Hwa Ha   +4 more
doaj   +1 more source

A MODEL FOR THE BASIC HELIX- LOOPHELIX MOTIF AND ITS SEQUENCE SPECIFIC RECOGNITION OF DNA [PDF]

Journal of Sciences, Islamic Republic of Iran, 1994
A three dimensional model of the basic Helix-Loop-Helix motif and its sequence specific recognition of DNA is described. The basic-helix I is modeled as a continuous ?-helix because no ?-helix breaking residue is found between the basic region and the ...
doaj  

TcMYC2a, a Basic Helix–Loop–Helix Transcription Factor, Transduces JA-Signals and Regulates Taxol Biosynthesis in Taxus chinensis

Frontiers in Plant Science, 2018
The multitherapeutic taxol, which can be obtained from Taxus spp., is the most widely used anticancer drug. Taxol biosynthesis is significantly regulated by jasmonate acid (JA), one of the most important endogenous hormones in land plants.
Meng Zhang, Meng Zhang, Xiaofei Jin, Xiaofei Jin, Ying Chen, Ying Chen, Mi Wei, Mi Wei, Weifang Liao, Weifang Liao, Shengying Zhao, Shengying Zhao, Chunhua Fu, Chunhua Fu, Longjiang Yu, Longjiang Yu   +15 more
doaj   +1 more source

ngn-1/neurogenin Activates Transcription of Multiple Terminal Selector Transcription Factors in the Caenorhabditis elegans Nervous System

G3: Genes, Genomes, Genetics, 2020
Proper nervous system development is required for an organism’s survival and function. Defects in neurogenesis have been linked to neurodevelopmental disorders such as schizophrenia and autism.
Elyse L. Christensen, Alexandra Beasley, Jessica Radchuk, Zachery E. Mielko, Elicia Preston, Sidney Stuckett, John I. Murray, Martin L. Hudson   +7 more
doaj   +1 more source

Genome-wide analysis of basic helix–loop–helix superfamily members related to anthocyanin biosynthesis in eggplant (Solanum melongena L.) [PDF]

PeerJ, 2019
The basic helix–loop–helix (bHLH) superfamily is considered the second largest transcription factor (TF) family. It plays regulatory roles in the developmental processes of plants and in their defense responses.
Shiyu Tian, Lujun Li, Min Wei, Fengjuan Yang   +3 more
doaj   +2 more sources

Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor.

Genes & Development, 1995
The insulin gene is one of the best paradigms of tissue-specific gene expression. It is developmentally regulated and is expressed exclusively in the pancreatic beta-cell.
F. Naya, C. M. Stellrecht, M. Tsai
semanticscholar   +1 more source

Arabidopsis Basic Helix-Loop-Helix Transcription Factors MYC2, MYC3, and MYC4 Regulate Glucosinolate Biosynthesis, Insect Performance, and Feeding Behavior[W][OPEN]

The Plant Cell, 2013
A triple mutant of MYC2, MYC3, and MYC4 transcription factors is devoid of glucosinolates and more sensitive to attack by a generalist insect. These MYCs physically interact with six MYB transcription factors (MYB28, MYB29, MYB34, MYB51, MYB76, and ...
Fabian Schweizer, Patricia Fernández-Calvo, Mark Zander, Mónica Díez-Díaz, Sandra Fonseca, G. Glauser, M. Lewsey, J. Ecker, R. Solano, P. Reymond   +9 more
semanticscholar   +1 more source

Iron-Binding E3 Ligase Mediates Iron Response in Plants by Targeting Basic Helix-Loop-Helix Transcription Factors1[OPEN]

Plant Physiology, 2014
An iron-binding protein causes degradation of proteins involved in the iron deficiency response. Iron uptake and metabolism are tightly regulated in both plants and animals.
Devarshi S. Selote, Rozalynne Samira, Anna Matthiadis, J. W. Gillikin, Terri A. Long   +4 more
semanticscholar   +1 more source

Structural and functional diversity of acidic scorpion potassium channel toxins. [PDF]

PLoS ONE, 2012
BACKGROUND: Although the basic scorpion K(+) channel toxins (KTxs) are well-known pharmacological tools and potential drug candidates, characterization the acidic KTxs still has the great significance for their potential selectivity towards different K(+)
Zong-Yun Chen, Dan-Yun Zeng, You-Tian Hu, Ya-Wen He, Na Pan, Jiu-Ping Ding, Zhi-Jian Cao, Mai-Li Liu, Wen-Xin Li, Hong Yi, Ling Jiang, Ying-Liang Wu   +11 more
doaj   +1 more source