Results 61 to 70 of about 107,836 (184)

Identification and expression analysis of the apple (Malus × domestica) basic helix-loop-helix transcription factor family

open access: yesScientific Reports, 2017
Basic helix-loop-helix (bHLH) proteins, which are characterized by a conserved bHLH domain, comprise one of the largest families of transcription factors in both plants and animals, and have been shown to have a wide range of biological functions ...
Jinhua Yang   +8 more
doaj   +1 more source

Fluorescence Resonance Energy Transfer (FRET) as a method to calculate the dimerization strength of basic Helix-Loop-Helix (bHLH) proteins

open access: yesBiological Procedures Online, 2004
Post-translational modifications such as phosphorylation play a vital role in the regulation of protein function. In our study of the basic Helix-loop-Helix (bHLH) transcription factor HAND1, we show that HAND1 is phosphorylated during the trophoblast ...
Centonze Victoria E.   +2 more
doaj   +1 more source

Tankyrase-1-mediated PARsylation directs TFEB partner switching to regulate selective Wnt target gene expression

open access: yesMolecules and Cells
: Wnt/β-catenin signaling coordinates developmental and oncogenic programs by modulating transcriptional networks. In addition to β-catenin, we previously identified transcription factor EB (TFEB)—a master regulator of lysosomal biogenesis and autophagy ...
Gahyeon Song   +2 more
doaj   +1 more source

Pleurotus ostreatus bHLH transcription factors regulate plant growth and development when expressed in Arabidopsis

open access: yesJournal of Plant Interactions, 2017
Fungi interact with plants in different ways in nature; however, it remains largely unclear if fungus gene may affect plant growth and development. Basic helix-loop-helix (bHLH) transcription factors are found in almost all organisms including plants and
Siyu Chen   +6 more
doaj   +1 more source

The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas

open access: yesDiabetes, 2015
Neurogenin3 (NEUROG3) is a basic helix-loop-helix transcription factor required for development of the endocrine pancreas in mice. In contrast, humans with NEUROG3 mutations are born with endocrine pancreas function, calling into question whether NEUROG3
P. McGrath   +4 more
semanticscholar   +1 more source

Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family

open access: yesComputational and Structural Biotechnology Journal, 2020
Engineering enzyme catalytic properties is important for basic research as well as for biotechnological applications. We have previously shown that the reshaping of enzyme access tunnels via the deletion of a short surface loop element may yield a ...
Martin Marek   +7 more
doaj   +1 more source

Caught Red-Handed: Rc Encodes a Basic Helix-Loop-Helix Protein Conditioning Red Pericarp in Rice[W][OA]

open access: yesThe Plant Cell Online, 2006
Rc is a domestication-related gene required for red pericarp in rice (Oryza sativa). The red grain color is ubiquitous among the wild ancestors of O. sativa, in which it is closely associated with seed shattering and dormancy.
Megan T Sweeney   +3 more
semanticscholar   +1 more source

The Basic/Helix-Loop-Helix Protein Family in Gossypium: Reference Genes and Their Evolution during Tetraploidization.

open access: yesPLoS ONE, 2015
Basic/helix-loop-helix (bHLH) proteins comprise one of the largest transcription factor families and play important roles in diverse cellular and molecular processes.
Qian Yan   +8 more
doaj   +1 more source

A basic helix-loop-helix transcription factor, PhFBH4, regulates flower senescence by modulating ethylene biosynthesis pathway in petunia

open access: yesHorticulture Research, 2015
The basic helix-loop-helix (bHLH) transcription factors (TFs) play important roles in regulating multiple biological processes in plants. However, there are few reports about the function of bHLHs in flower senescence.
Jing Yin   +5 more
semanticscholar   +1 more source

Diversification of DNA binding specificities enabled SREBP transcription regulators to expand the repertoire of cellular functions that they govern in fungi.

open access: yesPLoS Genetics, 2018
The Sterol Regulatory Element Binding Proteins (SREBPs) are basic-helix-loop-helix transcription regulators that control the expression of sterol biosynthesis genes in higher eukaryotes and some fungi.
Valentina Del Olmo Toledo   +3 more
doaj   +1 more source

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