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Evolution of a chloroplast-resident basic helix-loop-helix protein in tobacco plants
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Muscle basic helix-loop-helix proteins and the regulation of myogenesis
Current Opinion in Genetics and Development, 1992Significant progress has been made in defining the structural motifs that distinguish the muscle-specific from other basic helix-loop-helix proteins. Evidence is accumulating for multiple levels of regulation of the expression and action of the muscle basic helix-loop-helix factors.
Woodring E Wright
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Phylogenetic Analysis of Plant Basic Helix-Loop-Helix Proteins
Journal of Molecular Evolution, 2003The basic helix-loop-helix (bHLH) family of proteins is a group of functionally diverse transcription factors found in both plants and animals. These proteins evolved early in eukaryotic cells before the split of animals and plants, but appear to function in 'plant-specific' or 'animal-specific' processes.
Michael J, Buck, William R, Atchley
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Neofunctionalisation of basic helix−loop−helix proteins occurred when embryophytes colonised the land [PDF]
AbstractROOT HAIR DEFECTIVE SIX‐LIKE(RSL) genes control the development of structures from single cells at the surface of embryophytes (land plants) such as rhizoids and root hairs.RSLproteins constitute a subclass (VIIIc) of the basic helix–loop–helix (bHLH) classVIIItranscription factor family.The Charophyceae form the only class of streptophyte ...
Clémence Bonnot +2 more
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Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation
Development, 2000ABSTRACT An intracellular timer in oligodendrocyte precursor cells is thought to help control the timing of their differentiation. We show here that the expression of the Hes5 and Mash1 genes, which encode neural-specific bHLH proteins, decrease and increase, respectively, in these cells with a time course expected if the proteins are ...
T, Kondo, M, Raff
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Molecular Cloning and Characterization of DEC2, a New Member of Basic Helix-Loop-Helix Proteins
Biochemical and Biophysical Research Communications, 2001DEC1 is a basic helix-loop-helix (bHLH) protein related to Drosophila Hairy, Enhancer of split and HES, and involved in the control of proliferation and/or differentiation of chondrocytes, neurons, etc. We report here the identification and characterization of human, mouse and rat DEC2, a novel member of the DEC subfamily.
Katsumi Fujimoto +2 more
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Basic Helix–Loop–Helix Proteins Expressed During Early Embryonic Organogenesis
International Review of Cytology, 2004The basic helix-loop-helix proteins form a special group of transcription factors unique for the eukaryotic organisms. They are crucial for the embryonic development of many fundamental organ systems such as muscle, heart, central nervous system, hematopoiteic system, and many others.
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DNA Binding Specificity of the Basic-Helix-Loop-Helix Protein MASH-1
Biochemistry, 1995Despite the high degree of sequence similarity in their basic-helix-loop-helix (BHLH) domains, MASH-1 and MyoD are involved in different biological processes. In order to define possible differences between the DNA binding specificities of these two proteins, we investigated the DNA binding properties of MASH-1 by circular dichroism spectroscopy and by
Meierhan D +5 more
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DNA binding properties of basic helix-loop-helix fusion proteins of Tal and E47
Chemical Biology and Drug Design, 2001Abstract: The basic helix‐loop‐helix (bHLH) transcription factor Tal has been shown to form heterodimers with the ubiquitously expressed bHLH transcription factor E47 and thereby modulate gene expression. The absence of homodimeric Tal−DNA complexes had been attributed to the inability of Tal to homodimerize, but subsequent studies have shown that the ...
Indraneel Ghosh
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