Results 51 to 60 of about 5,521 (197)

A Non‐Canonical Core Transcriptional Regulatory Circuit Orchestrates Chromatin Reprogramming to Drive Osimertinib Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu, Zhenguo Liu, Lizhen Jiang, Andong Huang, Xinqing Lin, Xinyue Li, Bingyuan Liu, Shiwen Hu, Qiang Pan, Junjun Huang, Liyuan Yin, Liling Jiang, Wei Yi, Wenjun Mao, Yueyuan Zheng, Xianping Shi   +15 more
wiley   +1 more source

A highly accurate numerical method for solving boundary value problem of generalized Bagley‐Torvik equation

Mathematical Methods in the Applied Sciences, EarlyView.
A highly accurate numerical method is given for the solution of boundary value problem of generalized Bagley‐Torvik (BgT) equation with Caputo derivative of order 0<β<2$$ 0<\beta <2 $$ by using the collocation‐shooting method (C‐SM). The collocation solution is constructed in the space Sm+1(1)$$ {S}_{m+1}^{(1)} $$ as piecewise polynomials of degree at ...
Suzan Cival Buranay, Mtema James Chin, Nazim I. Mahmudov   +2 more
wiley   +1 more source

2‐Hydroxyisobutyrylation and Phosphorylation Crosstalk Guides Metastasis Prediction and Immunotherapy in Esophageal Squamous Cell Carcinoma

MedComm, Volume 7, Issue 7, July 2026.
This study deciphers the functional crosstalk between 2‐hydroxyisobutyrylation (Khib) and phosphorylation in driving esophageal squamous cell carcinoma (ESCC) metastasis. Through multi‐omics and machine learning, we developed a plasma protein signature for noninvasive detection of lymph node metastasis.
Junyi Li, Shujun Li, Xiaomei Yu, Qier Mu, Maowen Luo, Yuzhen Wang, Zhichao Liu, Chengwei Gu, Jiaxi Chen, Wangcheng He, Tong Yang, Yan He, Xiaoya Pei, Mao Lin, Zhigang Li, Jun Liu, Baosheng Zhao, Fan Zhang, Jinbao Liu, Bin Li, Wenwen Xu   +20 more
wiley   +1 more source

Application of basic hypergeometric series to stable analytic continuation

, 2000
Stable sampling formula using basic hypergeometric series for reconstructing analytic functions from exponentially spaced samples is considered.
Ali, Ismail, Vu Kim Tuan, Ismail Ali, Tuan, Vu Kim   +3 more
core   +1 more source

Theta Functions, Elliptic Hypergeometric Series, and Kawanaka's Macdonald Polynomial Conjecture

Symmetry, Integrability and Geometry: Methods and Applications, 2009
We give a new theta-function identity, a special case of which is utilised to prove Kawanaka's Macdonald polynomial conjecture. The theta-function identity further yields a transformation formula for multivariable elliptic hypergeometric series which ...
Robin Langer, Michael J. Schlosser, S. Ole Warnaar   +2 more
doaj   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, Volume 13, Issue 34, 19 June 2026.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Smartly Assembled near‐Micron RF‐Responsive Agents Bridge Transarterial Embolization and Immunothermal Potentiation

Advanced Science, Volume 13, Issue 31, 4 June 2026.
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu, Junkang Ding, Lingxiao Zhang, Zhou Tian, Cheng Zeng, Shaomin Zou, Wenjing Zhang, Tangye Zeng, Zhencang Gao, Zhouyi Sun, Gang Liu, Weiyu Chen, Zhe Tang   +12 more
wiley   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, Volume 13, Issue 31, 4 June 2026.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Summation formulae for elliptic hypergeometric series

, 2005
Several new identities for elliptic hypergeometric series are proved. Remarkably, some of these are elliptic analogues of identities for basic hypergeometric series that are balanced but not very-well ...
Warnaar, S. O.
core   +1 more source

A short proof of an identity of Sylvester

International Journal of Mathematics and Mathematical Sciences, 1999
We present two short proofs of an identity found by Sylvester and rediscovered by Louck. The first proof is an elementary version of Knuth's proof and is analogous to Macdonald's proof of a related identity of Milne.
Gaurav Bhatngar
doaj   +1 more source