Results 41 to 50 of about 15,589,079 (272)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing

open access: yesStem Cell Research & Therapy
The irreversible erosion of X-chromosome inactivation (XCI) due to repression of the long non-coding RNA XIST presents a major challenge for disease modeling and raises safety concerns for the clinical application of female human pluripotent stem cells ...
Nami Motosugi   +10 more
doaj   +1 more source

Aquatic life support course manual. 1st ed. [PDF]

open access: yes, 2022
Aquatic life support course manual (First edition) is the course manual created to provide aquatic rescue skills and knowledge for the medical personnel. The learning materials regarding aquatic rescue skills and the management of water related incidents
Hooi, Meng Sooi   +40 more
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Basic Newborn Life Support (BNLS) for members of the general public in natural disaster and conflict areas: A PHAID (PreHospital Aid) initiative

open access: yesInternational Journal of First Aid Education
Aim The PHAID (PreHospital Aid) initiative aims to reduce morbidity and mortality in regions affected by natural disasters or conflict by providing basic equipment and preemptive training to members of the public.
Abdul Qader Tahir Ismail
doaj   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Extracting physiologic and clinical data from defibrillators for research purposes to improve treatment for patients in cardiac arrest

open access: yesResuscitation Plus
Background: A defibrillator should be connected to all patients receiving cardiopulmonary resuscitation (CPR) to allow early defibrillation. The defibrillator will collect signal data such as the electrocardiogram (ECG), thoracic impedance and end-tidal ...
Trond Nordseth   +4 more
doaj   +1 more source

Effect of Contact-Restricted Basic Life Support Training During the Nation’s Contact Restriction Policy on Learning Outcomes

open access: yes, 2023
Suhattaya Boonmak, Polpun Boonmak Department of Anesthesiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, ThailandCorrespondence: Polpun Boonmak, Email bpolpu@kku.ac.thObjective: Basic life support (BLS) training aimed at building ...
Boonmak S, Boonmak P
core  

Basic Life Support in the Community Quiz

open access: yes, 2014
This is SCORM package for Basic Life Support in the Community ...
Kenny Smith, Win Ko
core   +6 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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