Results 41 to 50 of about 88,645 (280)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
A CONCEPTUAL MODEL OF THE LIFE CYCLE OF THE PROGRAM
Вісник Національного технічного університету «ХПÌ». Серія: Стратегічне управління, управління портфелями, програмами та проектами, 2016 A conceptual model of the life cycle of the program is proposed. This model is based on the value approach. As a resulting index, it uses a category of complex structural value.
Марія Костянтинівна СУХОНОС +2 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
, 2015 Bu çalışmada Üsküdar’daki 16.-18. yüzyıllarda şehir sosyal ve iktisadî yaşamı Osmanlı ferman, hüküm ve berât örneklerinden hareketle yansıtılmaya çalışılmış, İstanbul Ahkâm Defterleri ve Topkapı Sarayı Müzesi Osmanlı Arşiv Katalogu yararlanılan temel ...
FALAY, Nihat
core +1 more source
Frontiers in Psychiatry, 2020 Improving the subjective outcome of patients is an important target in the treatment of schizophrenia. Accordingly, the aim of the present study was to examine the association of factors deemed relevant in this context, i.e., premorbid functioning ...
Christine M. Hoertnagl +7 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Self-efficacy and outcome expectancies of secondary school students in performing basic life support
, 2021 Dumcke R, Rahe-Meyer N, Wegner C. Self-efficacy and outcome expectancies of secondary school students in performing basic life support. The Journal of Health, Environment, & Education.
Wegner, Claas ; https://orcid.org/ +2 more
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Frontiers in Psychology, 2016 We present the ToMenovela, a stimulus set that has been developed to provide a set of normatively rated socio-emotional stimuli showing varying amount of characters in emotionally laden interactions for experimental investigations of i) cognitive and ii)
Maike C. Herbort +15 more
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Brain and Behavior, 2021 The number of patients with chronic liver disease (CLD) is large. The social and economic burdens due to CLD have increased. The mental health problems of patients with CLD are prominent and deserve our attention and care.
Zhu Qin +4 more
doaj +1 more source