Results 51 to 60 of about 91,605 (239)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Analysis of need of community disabled elderly for home⁃based care and its influencing factors

open access: yesHuli yanjiu, 2020
ObjectiveTo investigate the needs of community disabled elderly for home-based care in Luzhou city and analyze its influencing factors.MethodsTotally 387 disabled old people selected by cluster sampling were investigated by the general data questionnaire
YANG Qian   +3 more
doaj  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

The clinical effect of gratitude extension-construction theory nursing program on bladder cancer patients with fear of cancer recurrence

open access: yesFrontiers in Oncology
ObjectiveTo explore the clinical effect of bladder cancer patients with Fear of Cancer Recurrence (FCR) after applying the gratitude extension construction theory nursing program.Methods168 patients with bladder cancer hospitalized in the Department of ...
Liping Qian   +6 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Efficacy and safety of carvedilol in combination with bronchodilators in patients with CHF of ischemic origin and COPD.

open access: yesКлиническая практика, 2019
Objective. To study the effectiveness of carvedilol, tiotropium bromide and indacaterol in complex therapy on clinical and functional parameters in patients with CHF of ischemic origin in combination with COPD. Material and methods. The study included
Vladimir V. Evdokimov   +2 more
doaj   +1 more source

ANALISIS BASIC RATING LIFE BEARING UCP 211-32 AKIBAT UNBALANCE MENGGUNAKAN METODE SKF DAN SIMULASI ANSYS PADA ALAT SIMULATOR BALANCING

open access: yesProsiding Seminar Nasional Teknologi Energi dan Mineral
Penelitian ini menganalisis lifetime dan fatigue life bearing UCP 211-32 akibat pengaruh unbalance serta variasi repeated load (2x–5x) pada alat simulator balancing. Metode yang digunakan meliputi perhitungan manual berbasis persamaan SKF dan simulasi numerik dengan ANSYS Workbench serta Discovery.
Rifandi Winadhi Mahardika   +2 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A shared structure for emotion experiences from narratives, videos, and everyday life

open access: yesiScience
Summary: Our knowledge of the diversity and psychological organization of emotion experiences is based primarily on studies that used a single type of stimulus with an often limited set of rating scales and analyses.
Yanting Han, Ralph Adolphs
doaj   +1 more source

Association of Age-Related Trends in Blood Pressure and Body Composition Indices in Healthy Adults

open access: yesFrontiers in Physiology, 2018
Purpose: Adiposity is one of the important determinants of blood pressure. The aim of this study is to evaluate the association between blood pressure and body composition indices throughout the whole lifespan of healthy adults.Patients and Methods: This
Wei Li   +12 more
doaj   +1 more source

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