Results 61 to 70 of about 88,645 (280)
Families, life events and family service delivery [PDF]
, 2012 Life events or transitions are understood to be circumstances that have an unsettling element for individuals (and from a systemic perspective, for family members also).
Lixia Qu +3 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
BMC Pregnancy and Childbirth, 2022 Background Pregnant women expecting twins are more likely to experience stress, which can lead to anxiety and depression. Our aim was to investigate the prevalence of prenatal anxiety and depressive symptoms in women with twin pregnancies and the ...
Ying Zhou +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Technical skills for basic scientists: hands on skills in basic science courses is appreciated and promotes employability/life skills which otherwise are difficult to demonstrate to employers [PDF]
, 2023 Students studying physiology undergraduate programmes often report aspirations of careers in clinical practice and clinical investigation (Steele et al., 2020), which are heavily skills-based and theoretically grounded.
Bagley, Liam, Hadgraft, Natasha
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Dimensioness method of assessing the conditions of thermal shock to the reactor vessel [PDF]
Ядерна фізика та енергетика, 2014 During the prolongation of the terms of the nuclear power plants operation the main issue is the substantiation of the possibility of the terms of the reactor vessel operation, which determines the economic necessity to con-tinue operating the unit as a ...
V. I. Skalozubov +3 more
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Analysis of need of community disabled elderly for home⁃based care and its influencing factors
Huli yanjiu, 2020 ObjectiveTo investigate the needs of community disabled elderly for home-based care in Luzhou city and analyze its influencing factors.MethodsTotally 387 disabled old people selected by cluster sampling were investigated by the general data questionnaire
YANG Qian +3 more
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Frontiers in OncologyObjectiveTo explore the clinical effect of bladder cancer patients with Fear of Cancer Recurrence (FCR) after applying the gratitude extension construction theory nursing program.Methods168 patients with bladder cancer hospitalized in the Department of ...
Liping Qian +6 more
doaj +1 more source