Results 61 to 70 of about 308 (188)

Knowledge rate of students of the nursing graduation course on Basic Life Support [PDF]

International Journal of Advanced Engineering Research and Science, 2020
Maicon de Araujo Nogueira, Luciane Caroline Ferreira de Azevedo Emim, Mayco Tadeu Vaz Silva, Marcilene Souza da Silveira, Karolayne Teles Costa, Letícia dos Santos Cruz, Lívia Karolina Silva de Oliveira, Thamyris Abreu Marinho, Simone Aguiar da Silva Figueira, Cinthya Lorena Bezerra Sarmanho, Márcio Almeida Lins, Elieni Santana de Abreu, Joyce da Silva Pantoja, Simone Batista da Silva dos Santos, Nathália Conceição Gonçalves Dalmacio, Fábyla D’ Tácia Brito Trindade, Eimar Neri de Oliveira Junior, Leliane do Nascimento do Espírito Santo, Adams Brunno Silva, Evelyn Amorim Coelho, Karla Christina Bernardes, Caroline Marinho Pereira, Bruna Camila Blans Moreira, Wanda Carla Conde Rodrigues, Glauber Marcelo Dantas Seixas, Viviane Ferraz Ferreira de Aguiar, Cinthya Lorena Bezerra Sarmanho, Eloísa Avelino de Sousa França, Elizabeth Valente Barbosa, Shirley Iara Martins Dourado, Tobias do Rosário Serrão, Manuella Matos de Azevedo, Tanymara Xavier de Morais, Dayhane Souza da Conceição, Izadora Larissa Cei Lima, Gabriel Itaparica de Oliveira, Manoel Vitor Martins Marinho, Deisiane da Silva Mesquita, Gabriela Oliveira da Silva, Brena do Socorro Correa de Oliveira, Widson Davi Vaz de Matos, Jasmin Stephany Savaris dos Santos, Otávio Noura Teixeira, Antonia Margareth Moita Sá   +43 more
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Physical Activity and College Students’ Subjective Well-being: The Mediating Roles of Basic Psychological Needs and Self-Efficacy

SAGE Open
Subjective well-being stands as a pivotal and comprehensive psychological indicator reflecting an individual’s quality of life, often intertwined with physical activity.
Zhou Nairun, Yue Yanli, Li Jiajing
doaj   +1 more source

Association of Age-Related Trends in Blood Pressure and Body Composition Indices in Healthy Adults

Frontiers in Physiology, 2018
Purpose: Adiposity is one of the important determinants of blood pressure. The aim of this study is to evaluate the association between blood pressure and body composition indices throughout the whole lifespan of healthy adults.Patients and Methods: This
Wei Li, Yan He, Yan He, Lili Xia, Xinghua Yang, Feng Liu, Jingang Ma, Zhiping Hu, Yajun Li, Dongxue Li, Jiajia Jiang, Guangliang Shan, Changlong Li   +12 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A Survey on Socio-Economic Factors in Relation to Quality of Life

جامعه شناسی کاربردی, 2009
This study has been performed by quantitative approach, survey method, and questionnaire technique.The theoretical framework has been synthesized from Maslow's theory of hierarchical needs, and humanecological-systems theory.
Habib Ahmadi, Alireza Eslam
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source