Results 71 to 80 of about 88,645 (280)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Knowledge rate of students of the nursing graduation course on Basic Life Support [PDF]

International Journal of Advanced Engineering Research and Science, 2020
Maicon de Araujo Nogueira, Luciane Caroline Ferreira de Azevedo Emim, Mayco Tadeu Vaz Silva, Marcilene Souza da Silveira, Karolayne Teles Costa, Letícia dos Santos Cruz, Lívia Karolina Silva de Oliveira, Thamyris Abreu Marinho, Simone Aguiar da Silva Figueira, Cinthya Lorena Bezerra Sarmanho, Márcio Almeida Lins, Elieni Santana de Abreu, Joyce da Silva Pantoja, Simone Batista da Silva dos Santos, Nathália Conceição Gonçalves Dalmacio, Fábyla D’ Tácia Brito Trindade, Eimar Neri de Oliveira Junior, Leliane do Nascimento do Espírito Santo, Adams Brunno Silva, Evelyn Amorim Coelho, Karla Christina Bernardes, Caroline Marinho Pereira, Bruna Camila Blans Moreira, Wanda Carla Conde Rodrigues, Glauber Marcelo Dantas Seixas, Viviane Ferraz Ferreira de Aguiar, Cinthya Lorena Bezerra Sarmanho, Eloísa Avelino de Sousa França, Elizabeth Valente Barbosa, Shirley Iara Martins Dourado, Tobias do Rosário Serrão, Manuella Matos de Azevedo, Tanymara Xavier de Morais, Dayhane Souza da Conceição, Izadora Larissa Cei Lima, Gabriel Itaparica de Oliveira, Manoel Vitor Martins Marinho, Deisiane da Silva Mesquita, Gabriela Oliveira da Silva, Brena do Socorro Correa de Oliveira, Widson Davi Vaz de Matos, Jasmin Stephany Savaris dos Santos, Otávio Noura Teixeira, Antonia Margareth Moita Sá   +43 more
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

The prevalence of, and risk factors for, loneliness in later life: a survey of older people in Great Britain

, 2005
This study examines the prevalence of loneliness amongst older people in Great Britain, and makes comparisons with the findings of studies undertaken during the last five decades.
Scambler, S, Bond, J, Victor, CR, Victor, Christina, Scambler, Sasha J., Bond, John, Scambler, Sasha; id_orcid, Victor, Christina R., Bowling, Ann, Bowling, A   +9 more
core   +1 more source

Reproducibility of the international spinal cord injury quality of life basic data set:an international psychometric study [PDF]

, 2019
STUDY DESIGN: Psychometric study.OBJECTIVES: To examine the reproducibility of the international spinal cord injury quality of life basic data set (QoL-BDS) in an international sample of community-dwelling adults with spinal cord injury or disease (SCI ...
Charlifue, Susan, Denise G. Tate, Post, Marcel W M, Forchheimer, Martin B, New, Peter W, Susan Charlifue, Peter W. New, Tate, Denise G, Marcel W. M. Post, Julia Maria D’Andréa Greve, Post, Marcel W M; id_orcid, Martin B. Forchheimer, D'Andréa Greve, Julia Maria   +12 more
core   +1 more source

A shared structure for emotion experiences from narratives, videos, and everyday life

iScience
Summary: Our knowledge of the diversity and psychological organization of emotion experiences is based primarily on studies that used a single type of stimulus with an often limited set of rating scales and analyses.
Yanting Han, Ralph Adolphs
doaj   +1 more source

Efficacy and safety of carvedilol in combination with bronchodilators in patients with CHF of ischemic origin and COPD.

Клиническая практика, 2019
Objective. To study the effectiveness of carvedilol, tiotropium bromide and indacaterol in complex therapy on clinical and functional parameters in patients with CHF of ischemic origin in combination with COPD. Material and methods. The study included
Vladimir V. Evdokimov, A. G. Evdokimova, E. N. Yushchuk   +2 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Life Cycle Climate Performance Model for Residential Heat Pump Systems

, 2012
A comprehensive analytical model using Excel and Visual Basic for Applications (VBA) has been developed to simulate life cycle climate performance (LCCP) for residential heat pumps. The LCCP model includes the direct impacts of refrigerant emissions, the
Muehlbauer, Jan, Zhang, Ming
core  

Physical Activity and College Students’ Subjective Well-being: The Mediating Roles of Basic Psychological Needs and Self-Efficacy

SAGE Open
Subjective well-being stands as a pivotal and comprehensive psychological indicator reflecting an individual’s quality of life, often intertwined with physical activity.
Zhou Nairun, Yue Yanli, Li Jiajing
doaj   +1 more source