Results 71 to 80 of about 8,297,014 (304)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Effect of Wind Environment on the response of Buildings in Oman
Sultan Qaboos University Journal for Science, 1998 An investigation has been carried out to study the effect of the wind parameters on the response of multistory buildings subjected to wind induced forces.
Mohammed Qamaruddin, Salem K. Al-Oraimi
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Recurrence Relations for the Equilibrium Means of Distributions Arising in Chemical Reactions
Sultan Qaboos University Journal for Science, 1997 In this paper we derive recurrence relations that describe how the equilibrium mean of the number molecules of a reactant varies with each of the parameters defining the initial state for four basic reversible chemical reactions.
E.K. Elsheikh
doaj +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Sultan Qaboos University Journal for Science, 1999 This paper presents a novel approach that predicts the strength and failure modes of jointed Glass Reinforced Polyester (GRP) samples under bending using Finite Element Method (FEM) and Artificial Neural Network (ANN). The mechanical behavior of fastened
C. Seibi Abdennour, M. Al-Alawi
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Effect of Compositional Grading On reservoir Performance
Sultan Qaboos University Journal for Science, 1996 In reservoirs with thickness exceeding fifty meters, compositional guiding has been found to cause significant variation in performance. Main fluid properties, governing the magnitude of reservoir performance, such as density; formation volume factor and
M. Al-Rumhy, A. Al-Bemani, F. Boukadi
doaj +1 more source
Viruses and Human Cancer: From Basic Science to Clinical Prevention
Recent Results in Cancer Research, 2021 semanticscholar +1 more source
A FRESH approach: Combining basic science and social good
Science immunology, 2018 A program to study HIV infection is empowering African women. A program to study HIV infection is empowering African women.
T. Ndung’u +3 more
semanticscholar +1 more source