Results 81 to 90 of about 6,234,437 (297)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Recurrence Relations for the Equilibrium Means of Distributions Arising in Chemical Reactions
Sultan Qaboos University Journal for Science, 1997 In this paper we derive recurrence relations that describe how the equilibrium mean of the number molecules of a reactant varies with each of the parameters defining the initial state for four basic reversible chemical reactions.
E.K. Elsheikh
doaj +1 more source
ARE BASIC SCIENCE AND BIOTECHNOLOGY COMPLEMENTARY ACTIVITIES? [PDF]
Enhancing agricultural productivity depends greatly on the management of information flows between basic and applied research. A framework is developed to examine the mutual relationship between molecular biological research and agricultural ...
Buccola, Steven T., Xia, Yin
core +1 more source
Researching sustainable agriculture: The role of values in systemic science [PDF]
, 2000 This paper presents a specific perspective on the science demarcation issue, the perspective of systemic science. A systemic science is a science that influences its own subject area.
Alrøe, Hugo Fjelsted
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Sultan Qaboos University Journal for Science, 1999 This paper presents a novel approach that predicts the strength and failure modes of jointed Glass Reinforced Polyester (GRP) samples under bending using Finite Element Method (FEM) and Artificial Neural Network (ANN). The mechanical behavior of fastened
C. Seibi Abdennour, M. Al-Alawi
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Effect of Compositional Grading On reservoir Performance
Sultan Qaboos University Journal for Science, 1996 In reservoirs with thickness exceeding fifty meters, compositional guiding has been found to cause significant variation in performance. Main fluid properties, governing the magnitude of reservoir performance, such as density; formation volume factor and
M. Al-Rumhy, A. Al-Bemani, F. Boukadi
doaj +1 more source
Federal Technology Transfer: Should We Build Subarus in Bethesda [PDF]
, 1990 A critical examination of a policy designed to encourage commercial exploitation of federally funded biomedical research. The author argues that the implementation of this policy threatens the integrity of basic science in ...
Harnett, Christopher J.
core +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source