Results 101 to 110 of about 1,653,806 (310)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cation Distribution in Natural Chromites from Oman
Sultan Qaboos University Journal for Science, 1996 Two specimens or natural chromite from the Oman ophiolite were studied using Mossbauer Spectroscopy (MS), X-ray Diffraction (XRD). and Scanning Electron Microscopy (SEM). The diffraction patterns obtained at room temperature showed that the two specimens
Z. Al-Alawi +7 more
doaj +1 more source
Enhancing the Comprehension of Basic Science Through Visual – Analogy
, 2018 The study investigated the effects of visual-analogy and teacher expository instructional strategies on pupil’s learning outcomes in Basic Science in Ondo State.
Sola, Agboola, Omowunmi
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Selection of Liner Materials and Design of Hazardous Water Facilities in Saudi Arabia
Sultan Qaboos University Journal for Science, 2001 Rapid development in Saudi Arabia has produced a broad spectrum of wastes. In the last two decades, several refineries and petrochemical industries have been established.
Sahel N. Abduljauwad, Ali M. Dakkak
doaj +1 more source
The Rise and Fall of Basic Science [PDF]
Frontiers in Systems Neuroscience, 2015 When you don't have a clue where to look for something you are interested in, such as cookies hidden in the kitchen, the best strategy may be a random search. If that something can be remotely sensed by you, e.g., smelled, then your search would be facilitated by adding gradient-sensing—if the gradient over two or more samples taken along a path is ...
openaire +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Internal basic research, external basic research and the technological performance of pharmaceutical firms. [PDF]
We evaluate the impact of basic research on pharmaceutical firms’ technological performance, distinguishing between internal basic research and the exploitation of external basic research findings.
Belderbos, Rene +2 more
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