Results 81 to 90 of about 8,297,014 (304)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Solvent Extraction of Uranium (VI) by Didodecylphosphoric Acid

Sultan Qaboos University Journal for Science, 1999
Solvent extraction of uranium(Vl) ion from perchlorate solution using didodecylphosphorie acid, DDPA, in toluene diluent was studied. The effects of stripping nitric acid concentration, stripping time, extraction time, DDPA concentration, pH, ionic ...
Khaled Mousa, Fawwaz Khalili
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Endocrine, Physiological and Histopathological Responses of Fish and their Larvae to Stress with Emphasis on Exposure to Crude Oil and Various Petroleum Hydrocarbons

Sultan Qaboos University Journal for Science, 2000
Various endocrine and physiological responses of fish exposed to forceful physical and chemical stimuli are reviewed with emphasis on the effects of crude oils and their hydrocarbon constituents.
A. Y. A. AL-Kindi, J.A. Brown, C.P. Waring   +2 more
doaj   +1 more source

The dark side of opioids in pain management: basic science explains clinical observation

PAIN Reports, 2016
Introduction: In the past 2 decades, opioids have been used increasingly for the treatment of persistent pain, and doses have tended to creep up. As basic science elucidates mechanisms of pain and analgesia, the cross talk between central pain and opioid
C. Rivat, J. Ballantyne
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The Stratigraphy and Structure of the Madamar-Salakh-Qusaybah Range and Natif-Fahud Area in the Oman Mountains

Sultan Qaboos University Journal for Science, 1996
Melanges and debris flows with clasts derived from the top of the Natih Formation found in shales in the base of the Aruma Group indicate that a period of Structural growth on the platform took place during Aruma deposition in the Late Cretaceous.
S.S. Hanna, J.D. Smewing
doaj   +1 more source

Decoupling of the minority PhD talent pool and assistant professor hiring in medical school basic science departments in the US

eLife, 2016
Faculty diversity is a longstanding challenge in the US. However, we lack a quantitative and systemic understanding of how the career transitions into assistant professor positions of PhD scientists from underrepresented minority (URM) and well ...
Kenneth D. Gibbs, J. Basson, Imam M. Xierali, David A. Broniatowski   +3 more
semanticscholar   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Nodulation of Medicago Sativa L. by Different Rhizobium Strains in the Sultanate of Oman

Sultan Qaboos University Journal for Science, 1997
Three native Rhizobium strains were isolated from Musandam. Buraimi and the Agricultural Experiment Station at Sultan Qaboos University in the Sultanate of Oman. An internationally known Rhizobium strain (TAI.
A.E. Elshafie, R. Victor, N. Al-Mugbali
doaj   +1 more source