Results 131 to 140 of about 4,317,506 (277)
Exploring Team-Based Teaching of Basic Sciences and Clinical Practice: Experiences of Pharmacy Students at a Malaysian Pharmacy School. [PDF]
Med Sci Educ, 2023 Tang KS, Maher S, Lee SWH.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Analysis of knowledge loss trend in basic clinical sciences throughout medical education [Letter]
Advances in Medical Education and Practice, 2019 Neelima Akter, Aysha KhalidFaculty of Medicine, St George’s Hospital Medical School, London, UKKnowledge retention is a challenge faced by many medical students in undergraduate teaching, and horizontal teaching of preclinical and clinical ...
Akter N, Khalid A
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Burnout Comparison between Clinical and Basic Sciences Faculty of a Medical School and Evaluation of Related Factors. [PDF]
Iran J Psychiatry, 2021 Haghighinejad H +5 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Medical Education During COVID-19 Pandemic: A Comparative Effectiveness Study of Face-to-Face Traditional Learning Versus Online Digital Education of Basic Sciences for Medical Students. [PDF]
Cureus, 2023 Omole AE, Villamil ME, Amiralli H.
europepmc +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source