Results 131 to 140 of about 14,127,790 (305)

Basic Medical Sciences - architect's drawing

, 1965
Bldg #: 211; Name(s): Basic Medical Sciences Building; Basic Medical Building Number 1; Function(s): Medical School; Completed: 11/30/67; Architect: W. C.
W. C. Kruger & Associates
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Editorial: Timing the Brain: From Basic Sciences to Clinical Implications. [PDF]

Front Hum Neurosci, 2022
Giglia G, Ognibene D, Bolognini N, De Tommaso M, Cappello F, Sardo P, Ferraro G, Brighina F.   +7 more
europepmc   +1 more source

Basic Medical Sciences - under construction

, 1965
Bldg #: 211; Name(s): Basic Medical Sciences Building; Basic Medical Building Number 1; Function(s): Medical School; Completed: 11/30/67; Architect: W. C.

core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Comparing the Attitudes of Basic Science Medical Students and Clinical Students Towards Their Fields and Their Career Futures at Urmia University of Medical Sciences [PDF]

آموزش پزشکی
Background and Objective: Worry about one's field of study has a severe negative impact on a student's mental health and academic performance, and this study aimed to compare the attitudes of basic science medical students with clinical students towards ...
Behrang Khafafi, Milad Alipor, Hamidreza Mehryar   +2 more
doaj  

How Science Educators Still Matter: Leveraging the Basic Sciences for Student Success. [PDF]

Med Sci Educ, 2022
Haudek SB, Bahner I, Belovich AN, Bonaminio G, Brenneman A, Brooks WS, Chinn C, El-Sawi N, Habal S, Haight M, Ikonne U, McAuley RJ, McKell D, Rowe R, Taylor TAH, Thesen T, Vari RC.   +16 more
europepmc   +1 more source

Basic Science and Alcoholism [PDF]

British Journal of Addiction, 1986
openaire   +2 more sources

Nils Hasselmo Hall (Basic Sciences Biomedical Engineering Building), Building File [PDF]

, 1985
This file contains material from 1985-2008.. (1985). Nils Hasselmo Hall (Basic Sciences Biomedical Engineering Building), Building File.
University of Minnesota. University Archives
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source