Results 151 to 160 of about 4,317,506 (277)

Basic Sciences

open access: yesJournal of Applied Oral Science, 2007
doaj   +1 more source

Evaluation of Educational Service Quality from the Perspective of Basic Medical Sciences Students at Mazandaran University of Medical Sciences [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Background and purpose: Considering the lack of comprehensive studies on the quality of educational services in medical sciences universities in the country, especially at the level of basic medical sciences education, this study was conducted to assess ...
Sajjad Saadatfard   +3 more
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Basic sciences curriculum in medical education

open access: yesJournal of Advances in Medical Education and Professionalism, 2013
Introduction: Traditional methods are generally used for teaching basic science courses at Shiraz Medical School. Such courses are taught during the first and second years of a seven-year medical program. The goal of this study was to analyze teachers
RITA REZAEE, VAHID KESHTKAR
doaj  

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Women in science: bridging gaps in basic sciences. [PDF]

open access: yesTrends Mol Med
Kumari B   +5 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

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