Results 91 to 100 of about 21,884 (318)
Resultant pressure distribution pattern along the basilar membrane in the spiral shaped cochlea [PDF]
arXiv, 2008 Cochlea is an important auditory organ in the inner ear. In most mammals, it is coiled as a spiral. Whether this specific shape influences hearing is still an open problem. By employing a three dimensional fluid model of the cochlea with an idealized geometry, the influence of the spiral geometry of the cochlea is examined.
arxiv
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Segmentation and reconstruction of the 3D geometry of the middle and inner ear
ITM Web of Conferences, 2017 The anatomical model of the ear is of great importance in the design of ossicular prosthesis, cochlear implant electrodes, as well as for the preoperative planning and navigation of surgery. By means of micro-computed tomography (micro-CT) and technology
Lu Yanfei
doaj +1 more source
Global well-posedness and multi-tone solutions of a class of nonlinear nonlocal cochlear models in hearing [PDF]
arXiv, 2003 We study a class of nonlinear nonlocal cochlear models of the transmission line type, describing the motion of basilar membrane (BM) in the cochlea. They are damped dispersive partial differential equations (PDEs) driven by time dependent boundary forcing due to the input sounds. The global well-posedness in time follows from energy estimates.
arxiv
Theoretical Analysis of Basilar Membrane Vibrations.
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C, 1995 The Cochlea is the principal sensory organ of the mammalian auditory system. High sensitivity and sharp tuning of a healthy cochlea and otoacoustic emissions (OAEs) has been discovered. In recent measurements, the outer hair cell (OHC) isolated in vitro is shown to be motile.
Kenji Ohyama +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
Signal processing of acoustic signals in the time domain with an active nonlinear nonlocal cochlear model [PDF]
arXiv, 2004 A two space dimensional active nonlinear nonlocal cochlear model is formulated in the time domain to capture nonlinear hearing effects such as compression, multi-tone suppression and difference tones. The micromechanics of the basilar membrane (BM) are incorporated to model active cochlear properties. An active gain parameter is constructed in the form
arxiv
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Investigations of Auditory Filters Based Excitation Patterns for Assessment of Noise Induced Hearing Loss [PDF]
arXiv, 2017 Noise induced hearing loss (NIHL) as one of major avoidable occupational related health issues has been studied for decades. To assess NIHL, the excitation pattern (EP) has been considered as one of mechanisms to estimate movements of basilar membrane (BM) in cochlea.
arxiv
Molecular Oncology, EarlyView.VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park +6 more
wiley +1 more source