Results 91 to 100 of about 1,994,891 (358)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Mathematical model for the basilar membrane as a two dimensional plate

Electronic Journal of Differential Equations, 1999
In this paper we present two mathematical models for the basilar membrane. In the first model the membrane is represented as an annular region. In the second model the basilar membrane is treated as a rectangular region.
H. Y. Alkahby
doaj  

The spatial buildup of nonlinear compression in the cochlea

Frontiers in Cellular Neuroscience
In the mammalian cochlea, the transduction from vibrations to inner hair cell receptor currents is preceded by a stage of mechanical pre-processing that involves a rapid, strongly nonlinear compression.
Kostas Kondylidis, Kostas Kondylidis, Anna Vavakou, Anna Vavakou, Marcel van der Heijden   +4 more
doaj   +1 more source

Dynamics of the tuning process between singers [PDF]

, 2004
We present a dynamical model describing a predictable human behavior like the tuning process between singers. The purpose, inspired in physiological and behavioral grounds of human beings, is sensitive to all Fourier spectrum of each sound emitted and it
Bolcatto, P. G., Urteaga, R.
core   +4 more sources

Basilar Membrane Displacement Related to Endolymphatic Sac Volume

The Laryngoscope, 2004
AbstractObjective: To demonstrate that the amount of basilar membrane displacement toward the scala tympani and its attachment to the bony wall of the scala tympani (i.e., interscalar septum) in hydropic temporal bones is related to the intraosseous endolymphatic sac volume.Study Design: A retrospective analysis of temporal bones from individuals with ...
Xenellis, JE, Linthicum, FH, Webster, P, Lopez, R   +3 more
openaire   +3 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

A Comprehensive Three-Dimensional Model of the Cochlea [PDF]

, 2003
The human cochlea is a remarkable device, able to discern extremely small amplitude sound pressure waves, and discriminate between very close frequencies.
Allaire, Allen, Allen, Beyer, Bogert, Chadwick, Clark, de Boer, Edward Givelberg, Fletcher, Geisler, Gold, Holmes, Inselberg, Johnstone, Julian Bunn, Kemp, Khanna, Kim, Kohllöffel, Kolston, Kolston, Lesser, Leveque, Loh, Manoussaki, Nuttall, Parthasarati, Peskin, Peskin, Peskin, Peterson, Ramamoorthy, Ranke, Rhode, Robles, Schroeder, Sellick, Siebert, Steele, Steele, Steele, Viergever, von Békésy, Zweig, Zwislocki, Zwislocki   +46 more
core   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Investigating the Performance of Gammatone Filters and Their Applicability to Design Cochlear Implant Processing System

Designs
Commercially available cochlear implants are designed to aid profoundly deaf people in understanding speech and environmental sounds. A typical cochlear implant uses a bank of bandpass filters to decompose an audio signal into a set of dynamic signals ...
Rumana Islam, Mohammed Tarique
doaj   +1 more source