Results 61 to 70 of about 21,884 (318)

Mathematical model for the basilar membrane as a two dimensional plate

Electronic Journal of Differential Equations, 1999
In this paper we present two mathematical models for the basilar membrane. In the first model the membrane is represented as an annular region. In the second model the basilar membrane is treated as a rectangular region.
H. Y. Alkahby
doaj  

Investigating the Performance of Gammatone Filters and Their Applicability to Design Cochlear Implant Processing System

Designs
Commercially available cochlear implants are designed to aid profoundly deaf people in understanding speech and environmental sounds. A typical cochlear implant uses a bank of bandpass filters to decompose an audio signal into a set of dynamic signals ...
Rumana Islam, Mohammed Tarique
doaj   +1 more source

A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ

Nature Communications, 2018
The sound envelope is important for speech perception. Here, the authors look at mechanisms by which the sound envelope is encoded, finding that it arises from distortion produced by mechanoelectrical transduction channels.
Alfred L. Nuttall, Anthony J. Ricci, George Burwood, James M. Harte, Stefan Stenfelt, Per Cayé-Thomasen, Tianying Ren, Sripriya Ramamoorthy, Yuan Zhang, Teresa Wilson, Thomas Lunner, Brian C. J. Moore, Anders Fridberger   +12 more
doaj   +1 more source

Heterogeneity in macrophages along the cochlear spiral in mice: insights from SEM and functional analyses

Frontiers in Cellular Neuroscience, 2023
The susceptibility of sensory cells to pathological conditions differs between the apical and basal regions of the cochlea, and the cochlear immune system may contribute to this location-dependent variability.
Celia Zhang, Celia Zhang, Mengxiao Ye, Peter Bush, Bo Hua Hu   +4 more
doaj   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Reduced equations for an active model of the hydroelastic waves in the cochlea [PDF]

arXiv, 2020
Building upon our earlier passive models for the cochlea, here we enhance the model with an active mechanism. Starting with a one-chamber simplification leading to a system of a time-dependent PDE in two spatial variables for the pressure coupled to a PDE in one spatial variable for the oscillation of the basilar membrane, we rigorously establish the ...
arxiv  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Three-dimensional tonotopic mapping of the human cochlea based on synchrotron radiation phase-contrast imaging

Scientific Reports, 2021
The human cochlea transforms sound waves into electrical signals in the acoustic nerve fibers with high acuity. This transformation occurs via vibrating anisotropic membranes (basilar and tectorial membranes) and frequency-specific hair cell receptors ...
Hao Li, Luke Helpard, Jonas Ekeroot, Seyed Alireza Rohani, Ning Zhu, Helge Rask-Andersen, Hanif M. Ladak, Sumit Agrawal   +7 more
doaj   +1 more source

A Brownian Energy Depot Model of the Basilar Membrane Oscillation with a Braking Mechanism [PDF]

arXiv, 2008
High auditory sensitivity, sharp frequency selectivity, and otoacoustic emissions are signatures of active amplification of the cochlea. The human ear can also detect very large amplitude sound without being damaged as long as the exposed time is not too long. The outer hair cells are believed as the best candidate for the active force generator of the
arxiv  

Fast frequency discrimination and phoneme recognition using a biomimetic membrane coupled to a neural network [PDF]

arXiv, 2020
In the human ear, the basilar membrane plays a central role in sound recognition. When excited by sound, this membrane responds with a frequency-dependent displacement pattern that is detected and identified by the auditory hair cells combined with the human neural system.
arxiv