Comparable outcomes with anti-thymocyte globulins versus basiliximab in kidney transplantation from controlled circulatory death donors [PDF]
Transplant InternationalDue to organ shortage, donation after circulatory death (DCD) has increased. As DCD kidney grafts have higher rates of delayed graft function (DGF), the French national protocol mandates the use of hypothermic machine perfusion and routine anti-thymocyte
Martin Deslais +36 more
doaj +2 more sources
Predictive Value of HLA-Derived T-Cell Epitope and B-Cell Epitope Matching Algorithms for Pancreas Transplant Outcomes. [PDF]
Clin TransplantABSTRACT Background Donor/recipient HLA molecular mismatches are predictive of kidney transplant outcomes. Their role in pancreas transplantation has not been well studied. Methods We conducted a retrospective cohort study in 281 pancreas (± kidney) transplant recipients during 2000–2018, followed for average 53.8 months.
Zare Z +8 more
europepmc +2 more sources
Cell Transplantation, 2012 Basiliximab is a recently developed immunosuppressive agent for the prevention of acute allograft rejection in renal transplant recipients. The combination use of basiliximab and a calcineurin inhibitor was suggested to be more effective in comparison to
Kentaro Sugiyama +2 more
exaly +2 more sources
Comparison of chimeric mouse-human and humanized anti-CD25 monoclonal antibodies for steroid-refractory acute graft-versus-host disease [PDF]
Frontiers in ImmunologyIntroductionSteroid-refractory acute graft-versus-host disease (SR-aGVHD) represents a severe and persistent complication that can arise following allogeneichematopoietic stem cell transplantation (allo-HSCT).
Xinhui Zheng +13 more
doaj +2 more sources
Cell TransplantationBasiliximab is an important treatment for steroid-refractory acute graft-versus-host disease (SR-aGVHD). We performed this retrospective study to evaluate the efficacy and safety of basiliximab treatment in SR-aGVHD patients following matched sibling ...
Xinya Jiang +2 more
exaly +2 more sources
Retrospective comparison of two distinct dual-induction strategies in pediatric kidney transplantation: three doses vs. a single dose of rabbit antithymocyte globulin, each combined with two basiliximab doses [PDF]
Frontiers in PediatricsBackgroundWe retrospectively compared two distinct dual-induction strategies in pediatric kidney transplantation.MethodsPatients transplanted at our center prior to 15 February 2020 were scheduled to receive three doses of rabbit antithymocyte globulin ...
Gaetano Ciancio +13 more
doaj +2 more sources
Impact of Induction Therapy in Low Immunological Risk Simultaneous Pancreas-Kidney Transplantation [PDF]
Transplant InternationalT-cell depleting agents and IL-2 receptor blockers are the most common induction therapies in simultaneous pancreas-kidney transplantation (SPKT), but the optimal choice remains debated.
Enrique Montagud-Marrahi +17 more
doaj +2 more sources
Evaluating the Role of Basiliximab Induction in Simultaneous Liver–Kidney Transplantation: A Multicenter Propensity-Score-Matched Analysis [PDF]
AntibodiesIntroduction: Simultaneous liver–kidney (SLK) transplant recipients are considered at lower immunologic risk than kidney-alone recipients, so steroid-only induction is often used.
Avery Koi +5 more
doaj +2 more sources
Induction Strategies in Lung Transplantation: Alemtuzumab vs. Basiliximab a Single-Center Experience
Frontiers in Immunology, 2022 BackgroundInduction therapy is used in about 80% of lung transplant centers and is increasing globally. Currently, there are no standards or guidelines for the use of induction therapy.
Masashi Furukawa +10 more
doaj +1 more source
Frontiers in Oncology, 2022 We aimed to identify the characteristics of immune reconstitution (IR) in patients who recovered from steroid-refractory acute graft-versus-host disease (SR-aGVHD) after basiliximab treatment. A total of 179, 124, 80, and 92 patients were included in the
Dao-Xing Deng +18 more
doaj +1 more source