Results 41 to 50 of about 9,749 (194)

Basiliximab for early perioperative transplant-associated thrombotic microangiopathy after lung transplantation: a case report

Surgical Case Reports, 2022
Background Thrombotic microangiopathy is a syndrome characterized by microangiopathic hemolytic anemia and platelet aggregation, which is caused by endothelial injury, microcirculation thrombosis, and fibrin deposition.
Naohiro Ijiri, Masaaki Sato, Chihiro Konoeda, Kazuhiro Nagayama, Jun Nakajima   +4 more
doaj   +1 more source

Meta-Analysis of Interleukin-2 Receptor Antagonists as the Treatment for Steroid-Refractory Acute Graft-Versus-Host Disease

Frontiers in Immunology, 2021
Acute graft-versus-host disease (aGVHD) is a major complication after allogeneic hematopoietic stem cell transplantation (HSCT). Corticosteroid is the first-line treatment for aGVHD, but its response rate is only approximately 50%.
Meng-Zhu Shen, Jing-Xia Li, Jing-Xia Li, Xiao-Hui Zhang, Lan-Ping Xu, Lan-Ping Xu, Yu Wang, Kai-Yan Liu, Xiao-Jun Huang, Xiao-Jun Huang, Xiao-Jun Huang, Shen-Da Hong, Xiao-Dong Mo, Xiao-Dong Mo   +13 more
doaj   +1 more source

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

Journal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali, Jing Kang, Simon Haworth, Alessandro Polizzi, Gaetano Isola   +4 more
wiley   +1 more source

Evaluation of Antithymocyte Globulin and Basiliximab as Induction Therapy in Kidney Transplant Recipients [PDF]

, 2023
Background The roles of induction and maintenance therapies are becoming increasingly critical in promoting the long-term success of renal transplants and the reduction of post-surgery acute rejection.
Herdrich, Kyle, Bhalla, Arnav, Katasani, Hamsini   +2 more
core   +1 more source

Clinical Significance of Organ Preservation Fluid Cultures in Pediatric Abdominal Solid Organ Transplantation

Transplant Infectious Disease, EarlyView.
In this pediatric abdominal solid organ transplant cohort, preservation fluid‐related infections were rare but occurred in infant liver transplant recipients whose preservation fluid cultures grew pathogenic organisms. These findings suggest that routine bacterial preservation fluid cultures may be most useful for identifying clinically significant ...
Hassan A. Jamal, Yong K. Kwon, Pamela L. Valentino, Jodi M. Smith, Patrick J. Healey, Zheyi Teoh   +5 more
wiley   +1 more source

Efficacy and safety of basiliximab in pediatric renal transplant patients receiving cyclosporine, mycophenolate mofetil, and steroids

, 2008
BACKGROUND: Basiliximab, a monoclonal CD25 antibody has proofed effective in reducing acute rejection episodes in adults in various immunosuppressive regimens. The effect of basiliximab in the pediatric population is controversial. METHODS: In a 12-month,
Schwarke, Dieter, Leichter, Heinz, Toenshoff, Burkhard, Wygoda, Simone, Zimmerhackl Lothar, B., Cochat, Pierre, Hoppe, Bernd, Bulla, Monika, Montoya, Carmen, Klaus, Günter, Mihatsch Michael, J., Fischer, Wolfgang, Krauss, Manuela, Fehrenbach, Henry, Misselwitz, Joachim, Foulard, Michel, Pape, Lars, Höcker, Britta, Hoyer Peter, F., Offner, Gisela, Neuhaus Thomas, J., Querfeld, Uwe, Plank, Christian, Jungraithmayr Therese, C., Latta, Kay, Müller-Wiefel Dirk, E.   +25 more
core   +2 more sources

The Association of Pretransplant CD4 Count With Post‐Kidney Transplant Infectious Outcomes Among Persons With HIV

Transplant Infectious Disease, EarlyView.
In this multi‐center study comparing persons with HIV with pre‐kidney transplant CD4 < 350 cells/µL to those with ≥ 350 cells/µL, we found no difference in relative risk of infection in the first year‐post kidney transplant, 5‐year graft survival, and 5‐year overall survival.
Rebecca H. Burns, Sara Booth, Christin Rogers Marks, Christine M. Durand, Jonathan Hand, Maheen Z. Abidi, Maricar Malinis, Brittany Barnaba, Martha Pavlakis, Douglas Krakower, Carolyn D. Alonso, Audrey Le‐Mahajan   +11 more
wiley   +1 more source

A benefit-risk assessment of basiliximab in renal transplantation

, 2004
Interleukin-2 (IL-2) and its receptor (IL-2R) play a central role in T lymphocyte activation and immune response after transplantation. Research on the biology of IL-2R allowed the identification of key signal transduction pathways involved in the ...
MARCHETTI, PIERO, Mosca F., BOGGI, UGO, Del Chiaro M, VISTOLI, FABIO, DANESI, ROMANO, Del Tacca M, Signori S   +7 more
core   +1 more source

Cytomegalovirus–Cell‐Mediated Immunity Assays for the Prevention and Management of Cytomegalovirus in Transplant Recipients and Patients Receiving Cellular Therapies

Transplant Infectious Disease, EarlyView.
This review summarizes the emerging role of CMV‐specific cell‐mediated immunity assays in CMV risk prediction and individualized prevention strategies across SOT, HCT, and CAR‐T settings. ABSTRACT CMV cell–mediated immunity (CMV–CMI) testing has emerged as a promising tool to refine CMV risk stratification and inform prevention strategies in transplant
Elisa Ruiz‐Arabi, Madeleine R. Heldman, Laurie D. Snyder, Oriol Manuel, Eleftheria Kampouri   +4 more
wiley   +1 more source

BASILIXIMAB AND ANTI-THYMOCYTE GLOBULIN AS AN INDUCTION OF IMMUNOSUPPRESSION IN RECIPIENTS OF VASCULARIZED ORGAN TRANSPLANTS [PDF]

Introduction and Aim: The advancement of immunosuppressive therapy has significantly increased organ transplantations. Among immunosuppressive agents, basiliximab and anti-thymocyte globulin (ATG) are key in induction therapy.
Bartosz Żegleń, Monika Grudzień, Filip Szydzik, Dominika Nowak, Julia Tarnowska, Katarzyna Kozon, Adam Zarzycki, Marcin Sawczuk, Patryk Macuk, Aleksandra Gradek   +9 more
core   +1 more source