Results 51 to 60 of about 9,749 (194)

Impact of Letermovir on Voriconazole Concentrations in Lung Transplant Patients

Transplant Infectious Disease, EarlyView.
Concomitant letermovir was associated with lower voriconazole exposure and reduced attainment of commonly used efficacy thresholds in lung transplant recipients. Routine therapeutic drug monitoring after letermovir initiation is recommended, and empiric voriconazole dose escalation may be needed to avoid subtherapeutic exposure. ABSTRACT Background The
Leah Georgiades, Sunish Shah, Erin K. McCreary, Fernanda Silveira, Raman Venkataramanan, Vignesh Vasudevan, Ryan M. Rivosecchi   +6 more
wiley   +1 more source

Early monitoring of the human polyomavirus BK replication and sequencing analysis in a cohort of adult kidney transplant patients treated with basiliximab

Virology Journal, 2011
Background Nowadays, better immunosuppressors have decreased the rates of acute rejection in kidney transplantation, but have also led to the emergence of BKV-associated nephropathy (BKVAN). Therefore, we prospectively investigated BKV load in plasma and
Mischitelli Monica, Fioriti Daniela, Colosimo Maria, Barile Mario, Tinti Francesca, Mitterhofer Anna, Bellizzi Anna, Anzivino Elena, Chiarini Fernanda, Ferretti Giancarlo, Taliani Gloria, Pietropaolo Valeria   +11 more
doaj   +1 more source

Invasive Fungal Infections in Heart Transplants: A 10‐Year, Single Centre Retrospective Cohort Study From Subtropical Australia

Transplant Infectious Disease, EarlyView.
In this 10‐year retrospective cohort study of heart transplant recipients in subtropical Australia, we characterize the incidence and microbiological profile of invasive fungal infections, highlighting the underappreciated burden of late‐onset and non‐Aspergillus mold infections and the potential underdiagnosis of polymicrobial disease.
Angus Lane, Karen Hay, John McNamara, Alex Chaudhuri, Andrew Burke, Robert Horvath, Maryam Khorramshahi Bayat, Kanthi Vemuri   +7 more
wiley   +1 more source

Pharmacodynamic Analysis of Tofacitinib and Basiliximab in Kidney Allograft Recipients

, 2012
Background. The common gamma-chain (gamma(c)) cytokines signal through the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway and play pivotal roles in lymphocyte activation. We investigated the effect of immunosuppressive
Chan, G, Quaedackers, Monique, Mol, WM, Vafadari, Ramin, Kho, MM; id_orcid, Weimar, Willem, Kho, MM, Baan, Carla   +7 more
core   +1 more source

Serial Blood Microbiome Profiles in Kidney Transplant Recipients Reveal Evidence of Circulating Gut and Non‐Gut Derived Microbial DNA

Transplant Infectious Disease, EarlyView.
In this prospective cohort study, we profiled the blood microbiome in kidney transplant recipients over time. We detected a low abundance of microbial DNA in half of the blood specimens. In a small subset, we also detected gut bacterial taxa in the blood of kidney transplant recipients.
Alex DeVito, Ananda L. Kimm‐Drapeau, William J. Higgins, Mia Montecillo, Matthew N. Bernstein, Sheavonnie Wright, Carol Li, Isha Bal, Darshana M. Dadhania, Friederike Selbach, John R. Lee   +10 more
wiley   +1 more source

Comparison of Infectious and Rejection Outcomes in Postkidney Transplant Recipients Based on Induction Therapy: A Retrospective Observational Study

Indian Journal of Transplantation
Background: Renal transplantation is the preferred treatment for patients with end-stage renal disease. Induction immunosuppressive therapy, administered perioperatively, plays a crucial role in reducing acute rejection episodes. However, these therapies
Vijay Chander Bukka, M. Niranjan, Pallavi Uppal, Ankit Tiwari, M. Prasanna, Sidharth Herur, Swarnalatha Guditi   +6 more
doaj   +1 more source

Utility of induction agents in living donor kidney transplantation

Indian Journal of Transplantation, 2019
Aim: The outcome and long-term adverse events associated with induction agent use for living donor (LD) kidney transplantation (KT) in India were studied.
Radhika Chemmangattu Radhakrishnan, Gopal Basu, Anjali Mohapatra, Suceena Alexander, Anna T Valson, Shibu Jacob, Vinoi George David, Santosh Varughese, Tamilarasi Veerasami   +8 more
doaj   +1 more source

Evaluating anti-thymocyte globulin induction doses for better allograft and patient survival in Asian kidney transplant recipients

Scientific Reports, 2023
Anti-thymocyte globulin (ATG) is currently the most widely prescribed induction regimen for preventing acute rejection after solid organ transplantation. However, the optimal dose of ATG induction regimen in Asian kidney recipients is unclear.
Ye Eun Shim, Youngmin Ko, Jung Pyo Lee, Jin Seok Jeon, Heungman Jun, Jaeseok Yang, Myoung Soo Kim, Seong Jun Lim, Hye Eun Kwon, Joo Hee Jung, Hyunwook Kwon, Young Hoon Kim, Jungbok Lee, Sung Shin, the Korean Organ Transplantation Registry (KOTRY) study group   +14 more
doaj   +1 more source

Pediatric Guillain‐Barré Syndrome Post Organ Transplant: Acute and Chronic Complication Requiring High Index of Suspicion

Pediatric Transplantation, Volume 30, Issue 10, October 2026.
ABSTRACT Background Guillain‐Barré syndrome (GBS) is an acute, immune‐mediated polyradiculoneuropathy most often triggered by infections such as Campylobacter jejuni, Epstein–Barr virus (EBV), or cytomegalovirus (CMV). Although transplant‐associated GBS is recognized in adults, it remains rare in pediatric recipients, and distinguishing immune‐mediated
Liora Rabizadeh, Paola Pergami
wiley   +1 more source

Antiviral Resistance Associated With Multiple Mutations Occurring in Seasonal Influenza A(H3N2) Virus in a Patient Treated With Oseltamivir

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Our case highlights the importance of early diagnosis in respiratory illness and timely detection of drug resistance so that antiviral treatment can be initiated and modified, particularly for high‐risk groups. Vaccination and early, carefully dosed antiviral treatment are key to mitigating severe influenza cases, especially in ...
Saira Hussain, Christina Guo, Yi‐Mo Deng, Nikita Deshpande, Presa Chanthalavanh, Natalie Spirason, Lauren Burmas, Heidi Peck, Bradley J. Gardiner, Ian G. Barr   +9 more
wiley   +1 more source