Results 81 to 90 of about 1,380,984 (267)
, 2022 Basis risk arises when the writer of a contingent claim cannot trade in the underlying asset and must use a correlated proxy asset to hedge the contingent claim. Suppose the proxy asset is not perfectly correlated to the underlying. In that case, there is a risk that the hedge portfolio does not precisely track the contingent claim, which may lead to ...
openaire +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Editorial: Clinical and genetic determinants of diabetes and complications
Frontiers in Endocrinology, 2023 Sen Li +5 more
doaj +1 more source
Медицина в Кузбассе, 2022 The review is devoted to topical issues of the development of the concept of risk management research as a basis for understanding the reduction of risk events of pharmaceutical organizations.
Андрей Георгиевич Петров +6 more
doaj
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Biological basis of extensive pleiotropy between blood traits and cancer risk
Genome MedicineBackground The immune system has a central role in preventing carcinogenesis. Alteration of systemic immune cell levels may increase cancer risk. However, the extent to which common genetic variation influences blood traits and cancer risk remains ...
Miguel Angel Pardo-Cea +31 more
doaj +1 more source
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Designing and evaluating a composite climatic index to risk management in livestock insurance
Environmental and Sustainability IndicatorsThe livestock sector in Iran, which has a significant nomadic population, is highly vulnerable to climate change and drought. This high vulnerability increases the need for modern support tools such as insurance, as traditional insurance has proven ...
Mahnaz Kalantaripor +3 more
doaj +1 more source