Results 51 to 60 of about 1,508,946 (291)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Batch-normalized Recurrent Highway Networks
, 2017 Gradient control plays an important role in feed-forward networks applied to various computer vision tasks. Previous work has shown that Recurrent Highway Networks minimize the problem of vanishing or exploding gradients. They achieve this by setting the
Loui, Alexander +5 more
core +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
2018 26th Euromicro International Conference on Parallel, Distributed and Network-based Processing (PDP), 2018 Many scientific applications are in need to solve a high number of small-size independent problems. These individual problems do not provide enough parallelism and then, these must be computed as a batch. Today, vendors such as Intel and NVIDIA are developing their own suite of batch routines.
Valero-Lara, Pedro +6 more
openaire +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Mutis, 2019 La astaxantina es un carotenoide y antioxidante utilizado en la industria cosmética, farmacéutica y alimentaria. Se produce naturalmente en la microalga H. pluvialis cuando esta crece bajo efecto de factores de estrés, como la deficiencia de nutrientes y
Luisa Gómez +7 more
doaj +1 more source
Optimization of Batch and Semi-batch Reactors
, 2013 Abstract Batch and semi-batch reactors are widely used for fine chemical productions. The target in the fine chemical industry is to produce a high quality product and operational optimization is the key-element to match it. This work investigates how batch and semibatch reactors can be optimized in order to increase the yield of a desired product ...
E. Pahija +2 more
openaire +4 more sources
Volatile fatty acids production from fermentation of secondary sewage sludge : a thesis presented in partial fulfillment of the requirements for the degree of Master of Engineering in Environmental Engineering [PDF]
, 2008 Sludge fermentation is used worldwide as an economical means to produce volatile fatty acids (VFA), which can be used as readily available carbon in biological nutrient removal (BNR) systems.
Banker, Sumit
core
Multiset Combinatorial Batch Codes
, 2017 Batch codes, first introduced by Ishai, Kushilevitz, Ostrovsky, and Sahai, mimic a distributed storage of a set of $n$ data items on $m$ servers, in such a way that any batch of $k$ data items can be retrieved by reading at most some $t$ symbols from ...
Silberstein, Natalia +2 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source