Results 61 to 70 of about 594,417 (290)

Entrainer selection for pressure swing batch distillation [PDF]

open access: yes, 2008
The feasibility of the separation of binary homoazeotropes with pressure swing batch distillation by the application of an entrainer is studied. The feasibility studies are based on the assumption of maximal separation and on the analysis of batch ...
Láng, Péter   +2 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Combinatorial batch codes [PDF]

open access: yes, 2008
In this paper, we study batch codes, which were introduced by Ishai, Kushilevitz, Ostrovsky and Sahai in [4]. A batch code specifies a method to distribute a database of [n] items among [m] devices (servers) in such a way that any [k] items can be ...
D. Stinson   +8 more
core   +1 more source

Nash Equilibrium and Social Optimization of Transactions in Blockchain System Based on Discrete-Time Queue

open access: yesIEEE Access, 2020
Blockchain technology has been used in many fields such as data management, cloud computing and Internet of Things with the features of decentralization, transparency and immutability. In order to study the performance of a blockchain system with a light-
Jiaxing Qi, Jing Yu, Shunfu Jin
doaj   +1 more source

EIGENVALUE EXPRESSION FOR A BATCH MARKOVIAN ARRIVAL PROCESS

open access: yesJournal of the Operations Research Society of Japan, 1997
Summary: Consider a batch Markovian arrival process (BMAP) as the counting process of an underlying process representing the state of environment. Such a process is useful for representing correlated inputs for example. They are used both as a modeling tool and as a theoretical device to represent and approximate superposition of input processes and ...
Nishimura, Shoichi, Sato, Hajime
openaire   +2 more sources

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Non-identifiability of the two state Markovian Arrival process [PDF]

open access: yes
In this paper we consider the problem of identifiability of the two-state Markovian Arrival process (MAP2). In particular, we show that the MAP2 is not identifiable and conditions are given under which two different sets of parameters, induce identical ...
Michael P. Wiper   +2 more
core  

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket   +14 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy