Results 41 to 50 of about 376,238 (287)

A discrete-time infinite-server batch arrival queue with application to serverless computing

Croatian Operational Research Review
Serverless computing systems behave like an infinite server queue, dynamically expanding the number of instances to handle incoming batch tasks. In serverless computing, to leverage its scalability, efficiency, and cost-effectiveness, it is essential to ...
Veena Goswami
doaj   +1 more source

On three methods for bounding the rate of convergence for some continuous–time Markov chains

International Journal of Applied Mathematics and Computer Science, 2020
Consideration is given to three different analytical methods for the computation of upper bounds for the rate of convergence to the limiting regime of one specific class of (in)homogeneous continuous-time Markov chains.
Zeifman Alexander, Satin Yacov, Kryukova Anastasia, Razumchik Rostislav, Kiseleva Ksenia, Shilova Galina   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

New extractive configuration separating azeotropic mixture in semi-batch way [PDF]

, 2006
A new variant of batch extractive distillation, the so-called inverse-fed batch extractive distillation is presented. The total amount of the entrainer is pre-loaded to the boiler, and the mixture charge to be separated is continuously fed to the column ...
Horvath, Laszlo, Fonyo, Zsolt, Lelkes, Zoltan, Stéger, Csaba, Rev, Endre, Meyer, Michel   +5 more
core   +1 more source

Causes of carcass condemnation in Norwegian aviary housed layers

Acta Veterinaria Scandinavica, 2023
Background Meat inspection data is commonly used to monitor health and welfare in commercial broiler production; however, less used in layers. Slaughterhouse records can provide insight into animal and herd health and identify important health and ...
Páll Gretarsson, Käthe Kittelsen, Randi Oppermann Moe, Ingrid Toftaker   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

New double column system for heteroazeotropic batch distillation [PDF]

, 2009
A new double column system (DCS) operated in closed mode is suggested for heterogeneous batch distillation. This configuration is investigated by feasibility studies based on the assumption of maximal separation and is compared with the traditional batch
Denes, F., Láng, Péter, Joulia, X., Joulia, Xavier, Modla, Gabor, Dénes, Ferenc   +5 more
core   +1 more source