Results 41 to 50 of about 43,933 (259)

Accelerating EdDSA Signature Verification with Faster Scalar Size Halving

open access: yesTransactions on Cryptographic Hardware and Embedded Systems
This paper establishes that the extended Euclidean algorithm (EEA) implemented in a division-free manner is faster than the Lagrange algorithm with a similar level of optimization when it comes to halving the size of scalars found in the equations of ...
Muhammad ElSheikh   +3 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Batch Signatures, Revisited

open access: yes
We revisit batch signatures (previously considered in a draft RFC and used in multiple recent works), where a single, potentially expensive, “inner” digital signature authenticates a Merkle tree constructed from many messages. We formalise a construction and prove its unforgeability and privacy properties.
Carlos Aguilar-Melchor   +7 more
openaire   +3 more sources

Batch verifying multiple RSA digital signatures

open access: yesElectronics Letters, 1998
A digital signature is analogous to an ordinary hand-written signature used in signing messages. RSA digital signatures have been adopted by Visa and Mastercard in the secure electronic transactions (SET) standard for providing security of electronic transfers of credit and payment information over the internet.
openaire   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Provably secure certificateless aggregate signature scheme in wireless roaming authentication

open access: yesTongxin xuebao, 2017
Certificateless aggregate signature (CLAS) schemes have been widely applied in resource-constrained wireless mobile networks,because they could not only realize batch validation but also solve the certificate management and key escrow problems.It was ...
Zhi-yan XU   +3 more
doaj   +2 more sources

Cryptanalysis and Improvement of an Anonymous Batch Verification Scheme for Mobile Healthcare Crowd Sensing

open access: yesIEEE Access, 2019
As an emerging application of smart healthcare, mobile healthcare crowd sensing (MHCS) has become a research hotspot. However, how to ensure the confidentiality and integrity of data and protect the privacy of user is still a challenge for MHCS.
Wenming Wang   +3 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

CHAM-CLAS: A Certificateless Aggregate Signature Scheme with Chameleon Hashing-Based Identity Authentication for VANETs

open access: yesCryptography
Vehicular ad hoc networks (VANETs), which are the backbone of intelligent transportation systems (ITSs), facilitate critical data exchanges between vehicles.
Ahmad Kabil   +3 more
doaj   +1 more source

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