Results 51 to 60 of about 154,933 (276)
Identification of a Qualitative Signature for the Diagnosis of Dementia With Lewy Bodies
Frontiers in Genetics, 2021 Background and purpose: Diagnosis of dementia with Lewy bodies (DLB) is highly challenging, primarily due to a lack of valid and reliable diagnostic tools. To date, there is no report of qualitative signature for the diagnosis of DLB. We aimed to develop
Shu Zhou +7 more
doaj +1 more source
Development of a Gd Loaded Liquid Scintillator for Electron Anti-Neutrino Spectroscopy
, 1999 We report on the development and deployment of 11.3 tons of 0.1% Gd loaded liquid scintillator used in the Palo Verde reactor neutrino oscillation experiment.
Andreas G Piepke +5 more
core +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Secure and Efficient Data Integrity Verification Scheme for Cloud-IoT Based on Short Signature
IEEE Access, 2019 The Internet of Things (IoT) is also known as the Internet of everything. As an important part of the new generation of intelligent information technology, the IoT has attracted the attention both of researchers and engineers all over the world ...
Hongliang Zhu +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Accelerating EdDSA Signature Verification with Faster Scalar Size Halving
Transactions on Cryptographic Hardware and Embedded SystemsThis paper establishes that the extended Euclidean algorithm (EEA) implemented in a division-free manner is faster than the Lagrange algorithm with a similar level of optimization when it comes to halving the size of scalars found in the equations of ...
Muhammad ElSheikh +3 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Provably secure certificateless aggregate signature scheme in wireless roaming authentication
Tongxin xuebao, 2017 Certificateless aggregate signature (CLAS) schemes have been widely applied in resource-constrained wireless mobile networks,because they could not only realize batch validation but also solve the certificate management and key escrow problems.It was ...
Zhi-yan XU +3 more
doaj +2 more sources