Results 41 to 50 of about 154,933 (276)

Improved blockchain-based ECDSA batch verification scheme

open access: yesFrontiers in Blockchain
IntroductionBlockchain technology has attracted much attention due to its decentralization, transparency and security. Initially applied in the financial field, it has now expanded to various fields such as Internet of Things (IoT), electronic cash and ...
Guangfu Wu, Jiandong Zhou, Xiaoyan Fu
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Data fusion protocol with source security for sensor networks

open access: yesTongxin xuebao, 2010
For the source security need,a digital signature scheme with aggregate signatures,data fusion and batch verification was proposed.Based on the proposed signature scheme and the homomorphic encryption technology,a data fusion protocol with secure sources ...
ZHANG Peng, YU Jian-ping, LIU Hong-wei
doaj   +2 more sources

A Qualitative Transcriptional Signature for Predicting Recurrence Risk for High-Grade Serous Ovarian Cancer Patients Treated With Platinum-Taxane Adjuvant Chemotherapy

open access: yesFrontiers in Oncology, 2019
Resistance to platinum and taxane adjuvant chemotherapy (ACT) is the main cause of the recurrence and poor prognosis of high-grade serous ovarian cancer (HGS-OvCa) patients receiving platinum-taxane ACT after surgery.
Yixin Liu   +11 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Fault Diagnosis of Batch Reactor Using Machine Learning Methods

open access: yesModelling and Simulation in Engineering, 2014
Fault diagnosis of a batch reactor gives the early detection of fault and minimizes the risk of thermal runaway. It provides superior performance and helps to improve safety and consistency. It has become more vital in this technical era.
Sujatha Subramanian   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Group-Signature and Group Session Key Combined Safety Message Authentication Protocol for VANETs

open access: yesIEEE Access, 2019
Anonymous authentication has significant contribution to privacy protection in safety message dissemination for Vehicular Ad Hoc Networks (VANETs); however, it suffers from heavy workload of vehicle revocation check and message signature verification ...
Chunhua Zhang   +4 more
doaj   +1 more source

Telomere-related prognostic biomarkers for survival assessments in pancreatic cancer

open access: yesScientific Reports, 2023
Human telomeres are linked to genetic instability and a higher risk of developing cancer. Therefore, to improve the dismal prognosis of pancreatic cancer patients, a thorough investigation of the association between telomere-related genes and pancreatic ...
Shengyang Chen   +8 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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