Results 41 to 50 of about 23,799 (218)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Applicability analysis of mixed oil length simulation using OLGA software for methanol-diesel batch transportation

You-qi chuyun
ObjectiveIncorporating methanol transport into refined oil pipelines can address the declining throughput of these pipelines while providing a safer transportation route for liquid hydrogen energy.
Diwu CHEN, Bohui SHI, Feng YAN, Jing GONG, Yubin WANG, Kai WEN, Zhengbing LI   +6 more
doaj   +1 more source

Parallel-Batch Scheduling and Transportation Coordination with Waiting Time Constraint

The Scientific World Journal, 2014
This paper addresses a parallel-batch scheduling problem that incorporates transportation of raw materials or semifinished products before processing with waiting time constraint.
Hua Gong, Daheng Chen, Ke Xu
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Online detection system and its application for mixed-oil interfaces in batch transportation of methanol via refined oil pipelines

You-qi chuyun
ObjectiveAccurate detection of quality indicators and mixed oil concentration at the mixed oil interface during the batch transportation of various media (gasoline, diesel, methanol, etc.) in refined oil pipelines is essential for identifying the mixed ...
Jinzhou SONG, Liang SHEN, Yi GUO, Xiaoyong DING, Hui SUN, Qiushi CAI, Shujuan QIU, Chunfeng SONG   +7 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Optimization of daily dispatching for multimodal transport of refined oil based on an integral solution philosophy

You-qi chuyun
ObjectiveIn recent years, the refined oil market has approached saturation. As a result, oil sales companies have increasingly focused on optimizing multimodal transport logistics.
Renfu TU, Rui QIU, Hao ZHANG, Shuai JIANG, Liyan HUANG, Guangtao FU, Xiang LU, Yongtu LIANG   +7 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Prospects for the construction of a methanol pipeline transportation system from the perspective of multi-energy integration and revitalization of stock assets

You-qi chuyun
ObjectiveGiven the challenges of reverse distribution and inefficient high-carbon logistics for green methanol in China, coupled with the risk of idle and stranded assets in existing oil pipelines amid peak oil consumption, it is crucial to revitalize ...
Renfu TU, Yongtu LIANG, Zhongshan TIAN, Guangtao FU, Xinwei WAN, Chunying LIU   +5 more
doaj   +1 more source