Results 151 to 160 of about 182,508 (303)

Deciphering Bax Dynamics: Regulation, Retrotranslocation, and Mitochondrial Interplay in the Commitment to Apoptosis: A Narrative Review. [PDF]

Health Sci Rep
Tanisha MH, Siddique MA, Ahmed Z, Mustafa N, Tasneem F.   +4 more
europepmc   +1 more source

Decidual macrophage‐mediated ferroptosis in trophoblasts leads to recurrent spontaneous abortion

iMeta, EarlyView.
Decidual macrophages from recurrent spontaneous abortion (RSA) patients promote trophoblast ferroptosis and impair trophoblast cell function. Mechanistically, the CXCL2/NF‐κB/HMOX1 axis mediates this effect. Conversely, trophoblasts co‐cultured with RSA decidual macrophages induce pro‐inflammatory macrophage polarization through IL‐6/JAK2/STAT3 ...
Xin Chen, Xueqin Ma, Pengcheng Pang, Heng Zhou, Ruohan Li, Yan He, Yan Zhang, Jing Yang, Qianlin Song, Qingsong Ye   +9 more
wiley   +1 more source

FABP3 Aggravates Cerebral Ischemia-Reperfusion Injury by Promoting Mitochondrial Lipid Accumulation and Enhancing BAX-Dependent Apoptosis. [PDF]

Cells
Zheng Y, Luo A, Fukunaga K, Liu Q, Guo Q.   +4 more
europepmc   +1 more source

A Passion for Birds: The Adventures of Nature Cinematographer John Bax

, 1996
For decades, John Bax has searched the world to bring us his beautiful images of nature, and particularly his passion, birds. A pioneer in nature cinematography, his work has been shared by millions.
Gorgas Science Foundation, Inc., Bax, John, Lof, Lawrence Victor   +2 more
core  

Metal‐dependent regulated cell death: Molecular architecture and translational frontiers

iMeta, EarlyView.
Intracellular metal dyshomeostasis orchestrates distinct regulated cell death programs, including iron‐driven ferroptosis, copper‐mediated cuproptosis, calcicoptosis, newly designated zincoptosis, mnoptosis, and coptosis. This review systematically delineates their molecular architectures—spanning from Sorafenib‐induced lipid peroxidation and ...
Haoliang Hu, Zhe Chen, Yaqi Li, Jiayi Peng, Jiangang Cao, Hong Zhou, Mengqi Wang, Yuejia Du, Hailin Wu, Huiqin Zhao, Shifang Huang, Dianmei Yu, Meiqing Liu, Olga V. Shevchenko, Natalia Yu. Matveeva, Yiyuan Yang, Kerui Huang, Deguan Lv, Junxia Min, Linxi Chen, Fudi Wang   +20 more
wiley   +1 more source

Upregulation of a Circular <i>BAX</i> Transcript in Breast Cancer Is Associated with Unfavorable Prognosis. [PDF]

Int J Mol Sci
Stafyla VK, Christodoulou S, Tsiakanikas P, Michalopoulos N, Danias N, Kokoropoulos P, Kontos CK, Arkadopoulos N.   +7 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Ubiquitin-Specific Protease 49 Interacts with Bax to Modulate Apoptosis. [PDF]

Int J Mol Sci
Choi HS, Kim SY, Kim SR, Baek KH.
europepmc   +1 more source

Structure of Bax [PDF]

Cell, 2000
Suzuki, Motoshi, Youle, Richard J., Tjandra, Nico   +2 more
openaire   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

Interdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu, Baoyuan Tang, Bei Xie, Haohua Deng, Haitang Yang, Lei Ma, Ziqing Zhang, Yicheng Ma, Xingyuan Ma, Shuaiyang Wang, Jing Li, Lei Zhao, Wengui Shi, Linjing Li   +13 more
wiley   +1 more source