Results 201 to 210 of about 145,032 (262)

Multiomics Insights Into AL Amyloidosis

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang   +6 more
wiley   +1 more source

Apoptosis signaling and cancer targeted therapy: from bench to bespoke. [PDF]

open access: yesTransl Cancer Res
Huang X   +5 more
europepmc   +1 more source

Deciphering the Chemotherapeutic Mechanism of Ferulic Acid: Insight Into the Role Against Multiple Human Cancers. [PDF]

open access: yesCancer Innov
Khatun S   +13 more
europepmc   +1 more source
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Bax: Addressed to kill

Biochimie, 2011
The pro-apoptototic protein Bax (Bcl-2 Associated protein X) plays a central role in the mitochondria-dependent apoptotic pathway. In healthy mammalian cells, Bax is essentially cytosolic and inactive. Following a death signal, the protein is translocated to the outer mitochondrial membrane, where it promotes a permeabilization that favors the release ...
Stephen Manon
exaly   +3 more sources

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