Results 21 to 30 of about 145,032 (262)

The influence of BCL2, BAX, and ABCB1 gene expression on prognosis of adult de novo acute myeloid leukemia with normal karyotype patients

Radiology and Oncology, 2023
Deregulation of the apoptotic process underlies the pathogenesis of many cancers, including leukemia, but is also very important for the success of chemotherapy treatment.
Pravdic Zlatko, Vukovic Nada Suvajdzic, Gasic Vladimir, Marjanovic Irena, Karan-Djurasevic Teodora, Pavlovic Sonja, Tosic Natasa   +6 more
doaj   +1 more source

Neferine improves oxidative stress and apoptosis in benign prostate hyperplasia via Nrf2-ARE pathway.

Redox Report, 2021
Background Progression of Benign Prostate hyperplasia (BPH) is vulnerable to oxidative stress (OS) and prostatic enlargement among the aging males through apoptosis deregulation.
Nabila Jahan, Apu Chowdhury, Ting Li, Ke Xu, Fen Wei, Sicen Wang   +5 more
doaj   +1 more source

Assessment of the in Vitro Effects of Folate Core–Shell Conjugated Iron Oxide Nanoparticles as a Potential Agent for Acute Leukemia Treatment

Frontiers in Bioscience-Landmark
Background and Objective: There is a growing need to comprehend the potential outcomes of nanoparticles (NPs) on human well-being, including their potential for detecting and treating leukemia.
Ghada M. Nasr, Osama M. Thawabieh, Randa M. Talaat, Mahmoud Moawad, Manal O. El Hamshary   +4 more
doaj   +1 more source

Investigating the mutual effects of autophagy and apoptosis in heart tissue of type 2 diabetic rats in interaction with aerobic exercise training and vitamin D3 injection [PDF]

فیزیولوژی ورزش و فعالیت بدنی
Background and Purpose: The interplay between autophagy and apoptosis is crucial in understanding heart health, particularly in the context of type 2 diabetes.
Hadi Golpasandi, Mohammad Rahman Rahimi, Slahadin Ahmadi   +2 more
doaj   +1 more source

Curcumin as an anti-proliferative agent in breast cancer through RASSF1A, Bax, and caspase-3 protein

Сибирский онкологический журнал, 2023
Background. Curcumin is a polyphenol that has pharmacological activity that can inhibit tumor cell growth and induce apoptosis through various mechanisms. However, the specifc mechanism of curcumin cytotoxicity remains controversial because of many anti-
N. A. Rahmah, H. Harliansyah, F. D. Suyatna, M. Kanoko, P. Rustamadji, J. Prihartono, A. Bustami, S. J. Haryono, B. S. Hernowo   +8 more
doaj   +1 more source

Mitochondrial Fusion: Bax to the Fussure [PDF]

Developmental Cell, 2011
Mitochondria can be organized into highly interconnected networks through continuous cycles of fission and fusion. A recent study by Hoppins et al. (2011) published in Molecular Cell now suggests that Bax, more commonly known for its role in apoptosis, can promote mitochondrial fusion in a Mitofusin 2-dependent manner.
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Chemical composition and cytotoxic properties of Clinacanthus nutans root extracts

Pharmaceutical Biology, 2017
Context: Clinacanthus nutans Lindau (Acanthaceae) is a medicinal plant that has been reported to have anti-inflammatory, antiviral, antimicrobial and antivenom activities.
Peik Lin Teoh, Angelina Ying Fang Cheng, Monica Liau, Fui Fui Lem, Grace P. Kaling, Fern Nie Chua, Bo Eng Cheong   +6 more
doaj   +1 more source

Markers of the Development of the Reconstruction Area Restenosis After Endovascular Interventions in Lower Limbs Arteries

Неотложная медицинская помощь, 2022
Restenosis of the reconstruction zone is one of the main postoperative complications of vascular reconstructions, which develops in 18–40% of cases and leads to an increase in the risk of limb loss to 20–25%. The search for new markers for predicting the
R. E. Kalinin, I. A. Suchkov, E. A. Klimentova, A. V. Shchulkin   +3 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source