Results 201 to 210 of about 221,308 (340)

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

1,8-Cineole Protects Against Liver Toxicity Induced by Aroclor-1254 in a Rat Model. [PDF]

J Biochem Mol Toxicol
Arshad H, Doğan MF, Zengin MN, Özmen Ö, Çiftçi O.   +4 more
europepmc   +1 more source

m6A‐modified EHD1 controls PD‐L1 endosomal trafficking to modulate immune evasion and immunotherapy responses in lung adenocarcinoma

Cancer Communications, EarlyView.
Abstract Background Eps15 homology domain (EHD) proteins, including EHD1 to EHD4, play vital roles in tumor progression. In this study, we aimed to investigate which specific EHD proteins, if any, are implicated in tumor immune evasion and immunotherapy response.
Fanglin Tian, Jian Huang, Weina Fan, Xin Li, Yuning Zhan, Kexin Zhu, Xiangyu Wang, Xin Hong, Xin Wang, Jin Ren, Ying Xing, Li Cai   +11 more
wiley   +1 more source

GSK-3 and BCL-XL inhibition mitigates the competitive advantage of APC-mutant colorectal cancer cells. [PDF]

Oncogenesis
Zhang L, Atencia Taboada L, Baglamis S, de Kroon M, Elshout C, Ramesh P, Helderman RFCPA, Torang A, Cameron K, van Driel MS, Wouters VM, van Neerven SM, Medema JP.   +12 more
europepmc   +1 more source

Direct Activation of Bax Protein for Cancer Therapy

Medicinal research reviews (Print), 2016
Zhiqing Liu, Ye Ding, Na Ye, Christopher T. Wild, Haiying Chen, Jia Zhou   +5 more
semanticscholar   +1 more source

Evaluation of apoptotic cells and immunohistochemical detection of FAS, FAS-L, Bcl-2, Bax, p53 and c-Myc in the skin of patients with chronic venous leg ulcers

, 1998
Heising
openalex   +2 more sources

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

Chemistry &Biodiversity, EarlyView.
ABSTRACT Cancer is a major global health concern. Therefore, new treatment options are needed. The phytochemicals have different chemical structures. It also exhibits several other biological activities. Therefore, these compounds are promising anticancer agents. This review aims to identify and assess new candidates for anticancer therapy. Researchers
Alaa A. A. Aljabali, Mohammad A. Obeid, Rasha M. Bashatwah, Esam Qnais, Omar Gammoh, Abdelrahim Alqudah, Vijay Mishra, Yachana Mishra, Mohammad Ahmed Khan, Suhel Parvez, Mohamed El‐Tanani, Taher Hatahet   +11 more
wiley   +1 more source

Effect of transport stress on apoptosis and autophagy in goat lung cells. [PDF]

Front Vet Sci
Zhuo Y, Hu Y, Jin Y, Ye T, Yang Y, Liu B, Zheng W, Ding S, Yang X, Zheng L, Hu W, Fang M, Yi W, Xing W.   +13 more
europepmc   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Editorial Expression of Concern: p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity. [PDF]

Cell Res
Wolff S, Erster S, Palacios G, Moll UM.
europepmc   +1 more source