Results 211 to 220 of about 150,507 (294)

Proteomic analysis confirmed that the occurrence of diabetic sarcopenia is related to autophagy and apoptosis. [PDF]

Front Endocrinol (Lausanne)
Wang T, Zhang L, Jiang Y, Zhao X, Hou K, Zhang Y, Yu N, Xu K.   +7 more
europepmc   +1 more source

A Naphthoquinone Compound Triggers Dna Damage-induced Apoptosis on Cholangiocarcinoma Through Upregulation of Bax and DR5 [PDF]

Gizem Bulut, Merve Kayis, Dilan Gezer, Zeliha Gökmen, Zelal Adıgüzel, Chiara Raggi, Engı̇n Ulukaya   +6 more
openalex   +1 more source

Tumor Microenvironments in Malignant Ovarian Germ Cell Tumors: MHC Class I Loss and T‐Cell Exhaustion in Dysgerminoma

Cancer Science, EarlyView.
Malignant ovarian germ cell tumor subtypes exhibit distinct tumor microenvironments. Dysgerminomas harbor abundant nonexhausted T cells, with progenitor exhausted T cells present in 60% of PD‐1–positive cases. However, MHC class I expression is lost across all analyzed subtypes, suggesting that restoring class I expression in dysgerminomas may enhance ...
Miya Nakashima, Takeshi Iwasaki, Yoshihiro Katayama, Masatoshi Shimo, Ken Takigawa, Naomi Shimada, Michiko Matsushita, Satoshi Kuwamoto, Shinya Sato, Masato Toya, Kohta Miyawaki, Koichi Akashi, Kiyoko Kato, Yoshinao Oda   +13 more
wiley   +1 more source

Optimization of insulin-like growth factor-1 supplementation enhances oocyte quality by modulating oxidative stress and apoptotic pathways during <i>in vitro</i> maturation of Kacang goat oocytes. [PDF]

Vet World
Widjiati W, Luqman EM, Darsini N, Aulanni'am A, Jaafar WNFBW, Utama S, Kurniawati DY, Shabira Z, Hendrawan VF.   +8 more
europepmc   +1 more source

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

, 2009
Tristan Gallenne, Fabien Gautier, Lisa Oliver, Éric Hervouet, Bélinda Noël, John A. Hickman, Olivier Geneste, Pierre‐François Cartron, François M. Vallette, Stéphen Manon, Philippe Juin   +10 more
openalex   +1 more source

Expression of the CXCR4 S338X Variant Improves Anti‐Leukemia Efficacy of Anti‐CD19 CAR‐T Cells

Cancer Science, EarlyView.
Under normal conditions, CXCL12 stimulation induces CXCR4 degradation. In contrast, CAR19‐T cells expressing the CXCR4 S338X variant maintain receptor stability and sustain ERK and AKT signaling, which supports T‐cell effector function, migration, and survival. Therefore, the enhanced anti‐leukemic activity is conferred by CXCR4 S338X expression in CAR‐
Yushu Mao, Xiaodan Wang, Chun‐Hui Jin, Zhifeng Wei, Qinghao Ding, Ke‐Ke Zhang, Bo‐Wen Dong, Kai‐Wen Zheng, Yufei Hou, Tao Zhang, Wen‐Jie Zhao, Zheng Hu, Yong‐Guang Yang   +12 more
wiley   +1 more source

Age-dependent effects of exercise on gut microbiota-mitochondria axis and cognitive function in aging mice. [PDF]

J Exerc Rehabil
Park SS, Park HS, Choi GR, Kim SH, Kim TW.   +4 more
europepmc   +1 more source

FB23‐2 and Cisplatin Synergize to Inhibit Head and Neck Squamous Cell Carcinoma by Targeting the XPF/ERCC1 Complex

Cancer Science, EarlyView.
FB23‐2 potentiates cisplatin's antitumor efficacy in head and neck squamous cell carcinoma by disrupting XPF/ERCC1 complex assembly and nuclear translocation, thereby suppressing DNA damage repair machinery and amplifying platinum‐induced tumor cell death.
Yaoqi Jiang, Hongshi Cai, Yue Zhu, Jianfeng Liang, Hongyu Li, Fan Song, Ziyi Wang, Jinsong Hou   +7 more
wiley   +1 more source