Results 221 to 230 of about 298,121 (314)

Long non-coding RNA GAS5 promotes neuronal apoptosis in spinal cord injury <i>via</i> the miR-21/PTEN axis. [PDF]

World J Orthop
Wang YJ, Zhi ZZ, Liu T, Kang J, Xu GH.
europepmc   +1 more source

Do Gadolinium‐Based Contrasts Represent a High Risk for Genotoxicity in Mammalian Cells? A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT The scientific rationale for this review stems from the increasing global use of gadolinium‐based contrast agents in medical imaging and the concerns over the long‐term environmental accumulation of gadolinium waste, which may pose biological risks.
Thiago Guedes Pinto, Rogerio Aparecido Dedivits, Daniel Araki Ribeiro   +2 more
wiley   +1 more source

Evaluation of Dietary Bioactive Agents Against Aflatoxin B1 and Ochratoxin A-Induced Duodenal Toxicity in Rats. [PDF]

Foods
Rafai S, Cimbalo A, Manyes L.
europepmc   +1 more source

Circ_0006646 Promotes the Progression of Osteoarthritis via Upregulating CDH11 Expression in an IGF2BP2‐Dependent Manner

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative osteoarthropathy with an unclear pathogenesis. Circular RNA (circRNA) has been reported to be associated with OA progression. This study aims to explore the role and potential mechanism of hsa_circ_0006646 in OA. Interleukin‐1β (IL‐1β)‐induced human chondrocytes were used as the cell model of OA. RT‐
Ming‐Yu Hua, Guo‐Liang Wang, Wen‐Hao Duan, Xiao‐Heng Tang   +3 more
wiley   +1 more source

Major Ozonated Autoheamotherapy Alleviates Skeletal Muscle Ischemia/Reperfusion Injury by Regulating Nrf2/HO‐1 Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Skeletal muscle ischaemia/reperfusion (I/R) injury remains a clinically significant condition characterized by muscular dystrophy. Although ozone therapy has shown protective potential against I/R injury in animal models of various organs including skeletal muscle, its precise mechanistic underpinnings require further elucidation.
Hui‐Zhuang Guo, Sheng‐Long Yu, Han‐Wei Chen   +2 more
wiley   +1 more source

Evaluation of Liposome Encapsulated Propolis Nanoparticles on Cell Proliferation and Apoptosis in A375 Melanoma Cancer Cell Line. [PDF]

Food Sci Nutr
Bidabad S, Ahmadpour Yazdi H, Zolghadr L, Valivand N, Gheibi N.   +4 more
europepmc   +1 more source

Dexmedetomidine Blocks the ERK Pathway by Inhibiting MAP3K8 to Achieve a Protective Effect in Lung Ischemia/Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung ischemia/reperfusion injury (LIRI) is a primary contributor to morbidity and mortality following lung transplantation. Dexmedetomidine (DEX) protects the lungs from I/R injury, but the underlying mechanisms remain uncertain. This paper examined the protective effect of DEX in LIRI and elucidated the potential regulation involved. LIRI was
Chun‐Huan Hu, Ru Qian, Yong‐Bo Wang, Lian‐Di Li, Chun‐Xing Miao   +4 more
wiley   +1 more source

Txnip/Trx Is a Potential Element in Regulating O-GlcNAc Modification in Photoreceptors to Alleviate Diabetic Retinopathy. [PDF]

Int J Mol Sci
Imdad L, Xu S, Meng Y, Bao K, Dong W, Yin X, Tong Y, Zhang W, Ren X, Kong L.   +9 more
europepmc   +1 more source

LncRNA SOX21‐AS1 Promotes the Progression of Pancreatic Cancer by Sponging miR‐9‐3p and Upregulating YOD1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pancreatic cancer (PC) is a highly aggressive malignancy of the digestive system. Recent studies have indicated that the long noncoding RNA SOX21‐AS1 is significantly upregulated in PC tissue samples. This study aims to elucidate the biological role and underlying molecular mechanisms of SOX21‐AS1 in PC progression. Quantitative real‐time PCR (
Han‐Bing Xu, Jian‐Tao Han, Cheng‐Peng Zhang, Bin Jiang   +3 more
wiley   +1 more source

Cardiomyocyte specific CD38 deletion protects heart from acute myocardial infarction by activating Sirt3 signaling pathway. [PDF]

Sci Rep
Wen K, Zhang YT, Zhao QH, Li Q, Zhao JL, Ding Q, Xiao YF, Guan XH, Jiang MX, Qian YS, Tian XL, Wang LF, Deng KY, Xin HB.   +13 more
europepmc   +1 more source