Results 271 to 280 of about 221,308 (340)

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

The emerging role of mitochondria in the pharmacological and toxicological effects of Tripterygium wilfordii Hook F: functions, targets and new therapeutic applications. [PDF]

Chin Med
Liu Z, Li D, Yang X, Chen X, Fu C.
europepmc   +1 more source

Integrin-Mediated Survival Signals Regulate the Apoptotic Function of Bax through Its Conformation and Subcellular Localization

, 2000
Andrew Gilmore, Anthony D. Metcalfe, Lewis H. Romer, Charles Streuli   +3 more
openalex   +1 more source

Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles

Interdisciplinary Materials, EarlyView.
This study explores the dysregulated “mitophagy–apoptosis–inflammation” axis in hypertrophic scar (HS) pathophysiology and proposes a synergistic therapy to restore microenvironmental homeostasis. By targeting mitochondrial dysfunction and inflammatory signaling, the strategy enhances scar regression, providing a novel clinical approach for HS ...
Shengjie Jiang, Jialiang Zhou, Liyun Wang, Xin Liu, Jiaming Sun, Yu Zhuang, Li Yu, Haiyan Li, Dejian Li, Zhaoyong Zou, Zhen Gao, Kaili Lin   +11 more
wiley   +1 more source

Examining the Impact of Sonodynamic Therapy With Ultrasound Wave in the Presence of Curcumin-Coated Silver Nanoparticles on the Apoptosis of MCF7 Breast Cancer Cells. [PDF]

IET Nanobiotechnol
Hormozi-Moghaddam Z, Neshasteh-Riz A, Taheri SM, Amini SM, Sedghinezhad E.   +4 more
europepmc   +1 more source

Apoptosis regulators of the Bcl‐2 family play a key role in chemoresistance of cholangiocarcinoma organoids

International Journal of Cancer, EarlyView.
What's New? Poor prognosis in cholangiocarcinoma (CCA) is attributed to late diagnosis and intrinsic chemoresistance. In particular, resistance mechanisms that suppress apoptosis limit the effectiveness of gemcitabine‐based regimens, which remain the standard treatment.
Wunan Mi, Gilles S. van Tienderen, Shaojun Shi, Amy Broeders, Kathryn Monfils, Henk P. Roest, Luc J. W. van der Laan, Monique M. A. Verstegen   +7 more
wiley   +1 more source

Medicinal plants: nutritional, immunological and therapeutic role in treating cancer-related malnutrition: a comprehensive review. [PDF]

Cancer Cell Int
El-Saadony MT, Alkafaas SS, Saad AM, Mohammed DM, Korma SA, Salem HM, Abd El-Mageed TA, Elsalahaty MI, Elkafas SS, Mosa WFA, Ahmed AE, Ibrahim EH, Alnadari F, Mathew BT, Abdelhamid AS, Allaban SF, Loutfy SA, Ghosh S, Assal HY, El-Tarabily MK, AbuQamar SF, El-Tarabily KA.   +21 more
europepmc   +1 more source

TNF-α Signals Apoptosis through a Bid-Dependent Conformational Change in Bax that Is Inhibited by E1B 19K

, 2000
Denise Perez, Eileen White
openalex   +1 more source

Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism

International Journal of Cancer, EarlyView.
Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello, Eric Felli, Teresa Musarra, Lorenzo Nevi, Annamaria Altomare, Jordi Gracia‐Sancho, Andrea Baiocchini, Simone Carotti   +7 more
wiley   +1 more source

Research progress on natural plant metabolites targeting apoptosis for endometriosis prevention and treatment: a systematic review. [PDF]

Front Pharmacol
Yu Y, Zhu Y, Gao M, Wang Y, Li S, Gou Y.
europepmc   +1 more source