Results 281 to 290 of about 298,121 (314)

Age‐Related Oxidative Stress and Mitochondrial Dysfunction in Lymph Node Stromal Cells Limit the Peripheral T Cell Homeostatic Maintenance and Function

Aging Cell, EarlyView.
Aging of the lymph node stromal cells limits their ability to support the survival and maintenance of peripheral naive T cells. The lymph node stromal cells are critical for providing the survival and trophic signals to peripheral naïve T cells, and after the early‐life thymic involution, these secondary lymphoid organ stromal microniches are decisive ...
Sandip Ashok Sonar, Ruchika Bhat, Heather L. Thompson, Christopher P. Coplen, Jennifer L. Uhrlaub, Mladen Jergovic, Janko Ž. Nikolich   +6 more
wiley   +1 more source

Anxiolytic Effects of <i>Cichorium intybus</i> L. Oligo-Polysaccharides by Modulating Gut Microbiota, Neuronal Signaling Pathways, and Neuroinflammation in Chronic Sleep Deprivation-Stressed Mice. [PDF]

Foods
Zhao Y, Zhang Y, Luo Y, Chen F, Qiang M, Liu M, Pan R, Chang Q, Wang N, Usmani MW, Jiang N, Liu X.   +11 more
europepmc   +1 more source

Quercetin Reduces Vascular Senescence and Inflammation in Symptomatic Male but Not Female Coronary Artery Disease Patients

Aging Cell, EarlyView.
In male patients undergoing CABG surgery, pretreatment with quercetin suppressed inflammaging and its associated inflammation, leading to improved endothelium‐dependent relaxation (measured ex vivo) and reducing new onset of post‐operative atrial fibrillation.
Pauline Mury, Olina Dagher, Annik Fortier, Ariel Diaz, Yoan Lamarche, Pierre‐Emmanuel Noly, Marina Ibrahim, Pierre Pagé, Philippe Demers, Denis Bouchard, Pierre‐Luc Bernier, Nancy Poirier, Emmanuel Moss, Nicolas Durrleman, Hughes Jeanmart, Michel Pellerin, Guillaume Lettre, Nathalie Thorin‐Trescases, Michel Carrier, Eric Thorin   +19 more
wiley   +1 more source

Unlocking the power of probiotics, postbiotics: targeting apoptosis for the treatment and prevention of digestive diseases. [PDF]

Front Nutr
Xie Q, Liu J, Yu P, Qiu T, Jiang S, Yu R.   +5 more
europepmc   +1 more source

Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches

Aging Cell, EarlyView.
Supplementation with the natural senolytic agent fisetin attenuated age‐related declines in physical function in mice. Better physical function with fisetin was accompanied by lower expression of cell senescence‐related genes. Fisetin treatment had comparable effects on physical function as genetic clearance of senescent cells and synthetic senolytic ...
Kevin O. Murray, Sophia A. Mahoney, Katelyn R. Ludwig, Jill H. Miyamoto‐Ditmon, Nicholas S. VanDongen, Nirad Banskota, Allison B. Herman, Douglas R. Seals, Robert T. Mankowski, Matthew J. Rossman, Zachary S. Clayton   +10 more
wiley   +1 more source

Synergistic Inhibition of Colon Cancer Cell Proliferation via p53, Bax, and Bcl-2 Modulation by Curcumin and Plumbagin Combination. [PDF]

ACS Omega
Ahmad I, Ahmad S, Samad MA, Adam AM, Zughaibi TA, Alhosin M, Shakil S, Khan MS, Alsaieedi AA, Kumer A, Tabrez S.   +10 more
europepmc   +1 more source

Matrix stiffness enhances viability, migration, invasion and invadopodia formation of oral cancer cells via PI3K/AKT pathway in vitro. [PDF]

Eur J Med Res
Zhang Z, Ren J, Tang K, Hu X, Liu J, Li C.   +5 more
europepmc   +1 more source

Effects of the modified "Yijing Fang" on semen quality and reproductive hormones in male yaks with kidney yang deficiency: a focus on mitochondrial apoptosis pathways. [PDF]

Anim Reprod
Chang P, Wang H.
europepmc   +1 more source

Antagonism of 5-HT7 Receptors as a Promising Target for Gastric Cancer via Apoptotic Pathway. [PDF]

J Biochem Mol Toxicol
Cinar I, Dincer B, Cadirci E, Kara S, Yildirgan MI, Halici Z, Palabiyik-Yucelik SS.   +6 more
europepmc   +1 more source

Identification of pyroptosis-associated gene to predict fibrosis and reveal immune characterization in non-alcoholic fatty liver disease. [PDF]

Sci Rep
Tu S, Jing X, Bu X, Zhang Q, Liao S, Zhu X, Guo Y, Sha W.   +7 more
europepmc   +1 more source