Results 291 to 300 of about 221,308 (340)

Circ_0006646 Promotes the Progression of Osteoarthritis via Upregulating CDH11 Expression in an IGF2BP2‐Dependent Manner

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative osteoarthropathy with an unclear pathogenesis. Circular RNA (circRNA) has been reported to be associated with OA progression. This study aims to explore the role and potential mechanism of hsa_circ_0006646 in OA. Interleukin‐1β (IL‐1β)‐induced human chondrocytes were used as the cell model of OA. RT‐
Ming‐Yu Hua, Guo‐Liang Wang, Wen‐Hao Duan, Xiao‐Heng Tang   +3 more
wiley   +1 more source

Oral Combined Probiotics Clostridium butyricum and Akkermansia muciniphila Inhibits the Progression of 4T1 Breast Cancer by Activating Bcl-2/Bax Pathway. [PDF]

Cancer Med
Li X, Hua D, Wu D, Hong W, Kang Y, Tang L, Yang Q, Wang X, Li B, Li R, Chen Z, Cui G.   +11 more
europepmc   +1 more source

Major Ozonated Autoheamotherapy Alleviates Skeletal Muscle Ischemia/Reperfusion Injury by Regulating Nrf2/HO‐1 Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Skeletal muscle ischaemia/reperfusion (I/R) injury remains a clinically significant condition characterized by muscular dystrophy. Although ozone therapy has shown protective potential against I/R injury in animal models of various organs including skeletal muscle, its precise mechanistic underpinnings require further elucidation.
Hui‐Zhuang Guo, Sheng‐Long Yu, Han‐Wei Chen   +2 more
wiley   +1 more source

The putative effector BgtE-20069a, secreted from Blumeria graminis f. sp. tritici, suppresses plant immunity to facilitate wheat infection. [PDF]

BMC Microbiol
Yan T, Cheng G, Zhai Y, Wu L, Gong S, Yu D, Yang L, Zeng F.   +7 more
europepmc   +1 more source

Dexmedetomidine Blocks the ERK Pathway by Inhibiting MAP3K8 to Achieve a Protective Effect in Lung Ischemia/Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung ischemia/reperfusion injury (LIRI) is a primary contributor to morbidity and mortality following lung transplantation. Dexmedetomidine (DEX) protects the lungs from I/R injury, but the underlying mechanisms remain uncertain. This paper examined the protective effect of DEX in LIRI and elucidated the potential regulation involved. LIRI was
Chun‐Huan Hu, Ru Qian, Yong‐Bo Wang, Lian‐Di Li, Chun‐Xing Miao   +4 more
wiley   +1 more source

<i>Centaurea lycaonica</i> Extracts Induce Apoptosis in HeLa Human Cervical Cancer Cells via Bax/Bcl-2 Modulation and Caspase Activation: An LC-HRMS-Based Study. [PDF]

Food Sci Nutr
Karaboğa Arslan AK, Eminoğlu S, Paşayeva L, Bozkurt NM, Tugay O.   +4 more
europepmc   +1 more source

Deletion of NFIA Leads to Activation of S100A7 and Inflammatory Response‐Induced Apoptosis of Keratinocytes in Oral Lichen Planus Progression

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT S100 calcium‐binding protein A7 (S100A7) has been implicated in psoriasis and other inflammatory diseases. However, the function of S100A7 in oral lichen planus (OLP), a chronic inflammatory disease, remains unclear. OLP was induced in mice by transplanting human OLP lesions into the backs of thymus‐free mice, and an in vitro cell model was ...
Maimaiti Tudi, Zumulaiti Aierken, Maihebubaimu Tuerxun, Maimaitituxun Tuerdi   +3 more
wiley   +1 more source

Bax Inhibitor MoBi-1 Is Required for Conidiation, Pathogenicity, and Stress Responses in <i>Magnaporthe oryzae</i>. [PDF]

J Fungi (Basel)
Meng S, Shen Y, Zhang D, Bao L, Cao H, Song G, Xie C, Jagernath JS, Shen G, Chen J.   +9 more
europepmc   +1 more source

LncRNA SOX21‐AS1 Promotes the Progression of Pancreatic Cancer by Sponging miR‐9‐3p and Upregulating YOD1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pancreatic cancer (PC) is a highly aggressive malignancy of the digestive system. Recent studies have indicated that the long noncoding RNA SOX21‐AS1 is significantly upregulated in PC tissue samples. This study aims to elucidate the biological role and underlying molecular mechanisms of SOX21‐AS1 in PC progression. Quantitative real‐time PCR (
Han‐Bing Xu, Jian‐Tao Han, Cheng‐Peng Zhang, Bin Jiang   +3 more
wiley   +1 more source

Kruppel-like factor 9 may regulate the inflammatory injury of chondrocytes by affecting NF-κB signaling. [PDF]

J Orthop Surg Res
Gu H, Han X, Ding Y, Deng J.
europepmc   +1 more source