Results 301 to 310 of about 221,308 (340)

Inhibition of miR‐499a‐5p Ameliorates Apoptotic and Autophagic Damage in Hypoxic Cardiomyocytes H9c2 Through Upregulation of ARGLU1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial infarction (MI), the most prevalent form of acute coronary syndrome, is often accompanied by cardiomyocyte apoptosis. In addition to apoptosis, autophagy plays a critical role in determining cardiomyocyte survival during MI. This study aimed to elucidate the regulatory role of miR‐499a‐5p in cardiomyocyte apoptosis and autophagy ...
Sha Wang, Hui‐Jun Wang, Shuo Pan
wiley   +1 more source

Tanshinone IIA induces oxidative stress in trophoblast cells and enhances copper dependent death. [PDF]

Sci Rep
Du J, Wang X, Zeng Y, Feng J, Yang L, Huang Y, Deng G.   +6 more
europepmc   +1 more source

Rhaponitin Reverses Cisplatin Resistance and Impairs Cancer Stemness Through HIF‐1α/MCT4/Wnt Pathway in Tongue Squamous Cell Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rhaponitin (Rha) possesses anti‐tumor activity and mediates the transcriptional activity of hypoxia‐inducible factor (HIF)‐1α that affects cisplatin (Cis) resistance. However, whether Rha can lessen Cis resistance in tongue squamous cell carcinoma (TSCC) by mediating HIF‐1α activity is unclear. Cis‐resistant SCC9 (SCC9‐CisR) cells were treated
Yuan Wu, Xiao‐Wen Wan, Lin Jiang, Wei Wang, Jia‐Jun Zhu, Yi‐Sen Shao   +5 more
wiley   +1 more source

The impact of Nrf2/HO-1, PD-L1/Bax/Bcl-2 and TNF-α/Il-6 signaling pathways in the ameliorative role of cordycepin against acrylamide-induced cardiac toxicity in rats. [PDF]

Sci Rep
Sedik AA, Hassan SA, Gouida MSO, Khalifa E.   +3 more
europepmc   +1 more source

Protective Effect of Hordenine on Concanavalin A-Induced Hepatic Injury. [PDF]

J Inflamm Res
Liu Y, Wang Y, Jiang M, Zhang Q, Yang M, Sun F, Xu Z, Liu T, Yao J.   +8 more
europepmc   +1 more source

Regulation of Human Lung Adenocarcinoma Cell Proliferation by LncRNA AFAP-AS1 Through the miR-508/ZWINT Axis. [PDF]

Int J Mol Sci
Kadasah SF, Alqahtani AMS.
europepmc   +1 more source

BDNF/proBDNF Interplay in the Mediation of Neuronal Apoptotic Mechanisms in Neurodegenerative Diseases. [PDF]

Int J Mol Sci
Mitrovic M, Selakovic D, Jovicic N, Ljujic B, Rosic G.   +4 more
europepmc   +1 more source

Atherosclerosis is associated with amyloid and tau pathology via blood-brain barrier dysfunction in the hippocampus of aged human brains. [PDF]

PLoS One
Jin Z, Liu N, Wei H.
europepmc   +1 more source

Expansion of Drosophila haemocytes using a conditional GeneSwitch driver affects larval haemocyte function, but does not modulate adult lifespan or survival after severe infection.

J Exp Biol
Hayman DJ, Morrin LM, Halder S, Phillips EJ, Simons MJP, Evans IR.   +5 more
europepmc   +1 more source

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Bax: Addressed to kill

Biochimie, 2011
The pro-apoptototic protein Bax (Bcl-2 Associated protein X) plays a central role in the mitochondria-dependent apoptotic pathway. In healthy mammalian cells, Bax is essentially cytosolic and inactive. Following a death signal, the protein is translocated to the outer mitochondrial membrane, where it promotes a permeabilization that favors the release ...
Thibaud T. Renault, Stéphen Manon
openaire   +3 more sources