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Allostery in BAX protein activation

Journal of Biomolecular Structure and Dynamics, 2016
BAX is a member of the proapoptotic BCL-2 family of proteins, which is involved in the regulation of the intrinsic pathway of apoptosis. In the process of apoptosis, BH3-only molecules activate cytosolic BAX. Activated BAX molecules insert into the mitochondrial outer membrane with their [Formula: see text]-helix and form oligomers that lead to ...
Hansi Zhang   +2 more
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HSP60, Bax, and Cardiac Apoptosis

Cardiovascular Toxicology, 2003
HSP60 has long been known as an important chaperonin and as having key folding functions within the mitochondria. However, it has now become evident that significant amounts of HSP60 are found in extra-mitochondrial locations. This extra-mitochondrial HSP60 in the heart has key anti-apoptotic functions. Extra-mitochondrial HSP60 complexes with both bax
Anne A Knowlton, Sanjiv Gupta
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Better Without Bax?

Science's STKE, 2007
At about age 50, depletion of ovarian follicles through apoptosis leads to the loss of cyclic ovarian function in women. Menopause, in turn, is believed to set the stage for various health problems. Although aging female mice do not undergo menopause, they experience depletion of ovarian follicles and health complications similar to those ...
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Bax at Length

The Musical Times, 1973
Colin Scott-Sutherland, Anthony Payne
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Bax as Poet

The Musical Times, 1980
Stephen Banfield   +2 more
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Reminiscences of Arnold Bax

The Musical Times, 1953
M. Montagu-Nathan, Arnold Bax
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A Reply to Belfort Bax

The Chesterton Review, 2008
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