Results 181 to 190 of about 145,032 (262)

Synthesis, Cytotoxicity, and Apoptosis‐Associated Cell Death Activity of an Isatin‐Containing Pyrimidine‐Derived Cu(II) Complex

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT A Cu(II) complex derived from a pyrimidine with the isatin group was synthesized and tested for its cytotoxic effects on A549 lung cancer and MCF‐7 breast cancer cell lines, as well as its effects on apoptosis‐associated cell death and cell cycle regulation in A549 cells. To evaluate cytotoxicity, MTT assays were performed at 24, 48, and 72 h,
Müjgan Kesik Oktay   +4 more
wiley   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli   +5 more
wiley   +1 more source

[<i>Qingda</i> Granules inhibit cerebral microvascular endothelial cell apoptosis in hypertensive mice by suppressing the P53 signaling pathway]. [PDF]

open access: yesNan Fang Yi Ke Da Xue Xue Bao
Lin Y   +8 more
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

open access: yesJSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz   +10 more
wiley   +1 more source

Bromelain as the enzyme of the future: A global bibliometric mapping of its applications and emerging trends

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto   +6 more
wiley   +1 more source

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen   +9 more
wiley   +1 more source

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