Results 71 to 80 of about 182,508 (303)
Characterization of Bax Pore Formation Using Fluorescence Techniques
Bax is a pro-apoptotic protein believed to permeabilize mitochondria during apoptosis. The mechanism Bax uses is not well understood. In this work, we use fluorescence techniques to shed light on how tBid activates Bax and we examine the topology of the
Lovell, Jonathan
core
СТРУКТУРНЫЕ ДЕТЕРМИНАНТЫ ВЫТЕСНЕНИЯ БЕЛКА Bax ИЗ КОМПЛЕКСА TOM/Bax БЕЛКОМ tBid ПРИ АПОПТОЗЕ
Structural factors that induce the proapoptotic activation of Bax by the protein TOM22 of the TOM complex and BH3-only protein tBid are established.
Valery G. Veresov +5 more
core +2 more sources
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao +10 more
wiley +1 more source
Effect of aerobic exercise on some factors of cardiac apoptosis in male rats
Background: Cardiac apoptosisplays an important role in myocardial diseases. Current evidence suggests that exercise training may modify some apoptosis-related signaling in myocardium.
Sadighi A +3 more
doaj
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun +6 more
wiley +1 more source
Previously, we designed DTCM-glutarimide as a novel anti-inflammatory agent inhibiting macrophage activation. It also showed anti-inflammatory activity in vivo.
A. Kaneda, Sh. Kh. Gantsev, K. Umezawa
doaj +1 more source
Variations sur Cadet Roussel [music] /
J.W.C. 3835 (Publisher number). For voice and piano.; Title from list t.p.; "Harmonisées par Arnold Bax, Frank Bridge, Eugène Goossens, John Ireland."; Individual sections within the work by each of the composers are marked with their initials.; Pl. no.:
Bax, Arnold, 1883-1953.
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Bax clustering under apoptotic stress.
A) Bax clustering- MCF-7 cells stably expressing GFP-Bax were incubated 6 hours at 37°C with the different conditions and nuclei were stained with Hoechst (100 ng/mL).
Yara Reis (187851) +7 more
core +1 more source
Evaluation of bcl-2, bax and c-erbB-2 Levels in Chronic Otitis Patients with or without Cholesteatoma [PDF]
Objective:The aim of this study was to evaluate bcl-2, bax, and c-erbB-2 expressions in primary and secondary acquired cholesteatoma and to indicate the role of apoptosis and accompanying increased cellular proliferation in the pathogenesis of ...
Emrah Sapmaz +7 more
core +1 more source
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng +7 more
wiley +1 more source

