Results 41 to 50 of about 1,298,041 (289)

BAYES RISKS OF ESTIMATORS OF ESTIMABLE PARAMETERS [PDF]

Bulletin of Mathematical Statistics, 1980
For the estimable parameter of degree 2, throughout this paper, we consider 02 with h2 such that h2(x, x) and h2(x, x)=0 for any x, yEX. As estimators of estimable parameters, U-statistics and differentiable statistical functions are well known. (See, for example, Hoeffding (1948) and von Mises (1947).) For an estimable parameter of degree 1, the U ...
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Bayesian and E-Bayesian estimation based on constant-stress partially accelerated life testing for inverted Topp–Leone distribution

Open Physics, 2023
Accelerated or partially accelerated life tests are particularly significant in life testing experiments since they save time and cost. Partially accelerated life tests are carried out when the data from accelerated life testing cannot be extrapolated to
Al Mutairi Aned, Alrashidi Afaf, Al-Sayed Neama Taher, Behairy Sarah Mohammad, Elgarhy Mohammed, Nassr Said G.   +5 more
doaj   +1 more source

Universal Bayes Estimators

The Annals of Statistics, 1978
Let $x_1, \cdots, x_n$ be i.i.d. random variables with a distribution depending on the real parameter. Under what conditions is a generalized Bayes estimator independent of the choice of the even loss function? The known answer to this question is that this independence holds if the posterior density is symmetric and unimodal.
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Statistical Analysis for Constant-Stress Accelerated Life Test With Weibull Distribution Under Adaptive Type-II Hybrid Censored Data

IEEE Access, 2019
In this paper, we discuss the point and interval estimates of the parameters from Weibull distribution based on adaptive Type-II progressively hybrid censored data in constant-stress accelerated life test using maximum likelihood estimation (MLE) methods
Wei Cui, Zaizai Yan, Xiuyun Peng
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Estimation of Rényi entropy of linear failure rate distribution based on Generalized Type- II Hybrid Censored Samples [PDF]

المجلة العلمية للدراسات والبحوث المالية والتجارية
Entropy is an essential term in statistical mechanics that was originally defined in the second law of thermodynamics. In this paper, we estimate the Rényi entropy measure of a linear failure rate distribution when data are generalized type-II hybrid ...
Dina Samir
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Asymptotic Behavior of Bayes' Estimates

The Annals of Mathematical Statistics, 1964
This paper extends some of the results obtained by Freedman [2]. In Section 1 a class of prior distributions on the space of all substochastic distributions on the positive integers is given, such that along almost all sample sequences the corresponding posterior distributions of the expectations of all bounded functions on the positive integers are ...
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Bayes Estimation with Convex Loss

The Annals of Mathematical Statistics, 1963
Let $X$ be a generalized random variable taking values in an abstract set $\mathscr{X}$ on which is defined an appropriate $\sigma$-field of subsets. Suppose that the distribution of $X$ depends on a real parameter $\Theta$ and that it is desired to estimate the value of $\Theta$ from an observation on $X$.
DeGroot, M. H., Rao, M. M.
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USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source