Results 61 to 70 of about 52,384 (263)

Statistical Analysis and Applications of Adaptive Progressively Type-II Hybrid Poisson–Exponential Censored Data

Axioms, 2023
A new two-parameter extended exponential lifetime distribution with an increasing failure rate called the Poisson–exponential (PE) model was explored.
Ahmed Elshahhat, Heba S. Mohammed
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Some results on Bayes estimation under Linex loss function [PDF]

Journal of Hyperstructures
In this paper, we introduced straightforward formulas for the Bayes risk linked to the Linex loss function, which we then applied to estimate parameters of the normal, Poisson, and fractional Weibull distributions.We aimed to investigate the development ...
Masoud Ganji, Fatemeh Gharari
doaj   +1 more source

Estimations For The Odd Weibull Distribution under Progressive Type-II Right Censored Samples

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2020
In this study, We introducedperformances Maximum Likelihood (ML) and Bayes estimation under LINEX, GENTROPYand SQUARED loss functions results concerning a progressively type-II censoredsamples for parameters of OddW distribution.
Gülcan Gencer, Kerem Gencer
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Hierarchical regression for multiple comparisons in a case-control study of occupational risks for lung cancer.

PLoS ONE, 2012
BackgroundOccupational studies often involve multiple comparisons and therefore suffer from false positive findings. Semi-Bayes adjustment methods have sometimes been used to address this issue.
Marine Corbin, Lorenzo Richiardi, Roel Vermeulen, Hans Kromhout, Franco Merletti, Susan Peters, Lorenzo Simonato, Kyle Steenland, Neil Pearce, Milena Maule   +9 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Bayesian and Classical Methods for Log Logistic Distribution: Exploring Upper Record Values in Bladder Cancer Remission Times

Journal of Statistical Theory and Applications (JSTA)
This research explores Bayesian and classical estimation methods for the Log Logistic distribution, focusing on upper record values in bladder cancer remission times.
Rabia Azeem, Muhammad Aslam, Tahir Mehmood   +2 more
doaj   +1 more source

A Note on the Bayes Estimation of Reliability for the Inverse Gaussian Distribution [PDF]

The Egyptian Statistical Journal, 1986
Bayes estimators of the reliability function of the inverse Gaussian distribution are obtained when λ, the scale parameter is known. The Bayes estimators are compared with the maximum likelihood and minimum variance unbiased estimators of reliability ...
S. Shaban
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source