Results 71 to 80 of about 832,071 (345)

On a Stress-Strength Model in Weibull Case [PDF]

The Egyptian Statistical Journal, 1996
In this paper three estimators for the reliability function P (Y < X), (MLE, UMVUE and Bayes estimators) are given when X and Y are two independent but not identically distributed Weibull random variables with common and known shape parameter.
M. Mahmoud
doaj   +1 more source

Bayesian Analysis for the Modified Frechet–Exponential Distribution with Covid-19 Application

Cumhuriyet Science Journal, 2023
In this manuscript, the maximum likelihood estimators and Bayes estimators for the parameters of the modified Frechet–exponential distribution. Because the Bayes estimators cannot be obtained in closed forms, the approximate Bayes estimators are computed
Neriman Akdam
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

PENERAPAN METODE SAE DENGAN PENDEKATAN EMPIRICAL BAYES BERBASIS MODEL BETA BINOMIAL PADA DATA BANGKITAN

Media Statistika, 2021
Small Area Estimation (SAE) is one of the statistical methods that used to estimate parameters of model from small subpopulations. Because of that, additional information is needed to predict these parameters that will result a more accurate predictive ...
Ferra Yanuar, Rahmatika Fajriyah, Dodi Devianto   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Classic and Bayes Shrinkage Estimation in Rayleigh Distribution Using a Point Guess Based on Censored Data

پژوهش‌های ریاضی, 2018
Introduction      In classical methods of statistics, the parameter of interest is estimated based on a random sample using natural estimators such as maximum likelihood or unbiased estimators (sample information).
azadeh kiapour
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Odds Ratios Estimation of Rare Event in Binomial Distribution

Journal of Probability and Statistics, 2016
We introduce the new estimator of odds ratios in rare events using Empirical Bayes method in two independent binomial distributions. We compare the proposed estimates of odds ratios with two estimators, modified maximum likelihood estimator (MMLE) and ...
Kobkun Raweesawat, Yupaporn Areepong, Katechan Jampachaisri, Saowanit Sukparungsee   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Empirical Bayes Estimators for Mean Parameter of Exponential Distribution with Conjugate Inverse Gamma Prior Under Stein’s Loss

Mathematics
A Bayes estimator for a mean parameter of an exponential distribution is calculated using Stein’s loss, which equally penalizes gross overestimation and underestimation.
Zheng Li, Ying-Ying Zhang, Ya-Guang Shi
doaj   +1 more source