Results 61 to 70 of about 832,071 (345)

On general maximum likelihood empirical Bayes estimation of heteroscedastic IID normal means

open access: yesElectronic Journal of Statistics, 2020
: We propose a general maximum likelihood empirical Bayes (GMLEB) method for the heteroscedastic normal means estimation with known variances. The idea is to plug the generalized maximum likelihood estimator in the oracle Bayes rule.
Wenhua Jiang
semanticscholar   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

© Hindawi Publishing Corp. AN IMPROVED BAYES EMPIRICAL BAYES ESTIMATOR [PDF]

open access: yes, 2001
Consider an experiment yielding an observable random quantity X whose distri-bution Fθ depends on a parameter θ with θ being distributed according to some distribution G0.
N. G. N. Prasad, R. J. Karunamuni
core  

A penalised data-driven block shrinkage approach to empirical Bayes wavelet estimation [PDF]

open access: yes, 2010
In this paper we propose a simple Bayesian block wavelet shrinkage method for estimating an unknown function in the presence of Gaussian noise. A data–driven procedure which can adaptively choose the block size and the shrinkage level at each resolution ...
Wang, Xue, Walker, Stephen G.
core   +1 more source

Extended linear empirical Bayes estimation [PDF]

open access: yes, 2000
In this paper, the linear empirical Bayes estimation method, which is based on approximation of the Bayes estimator by a linear function, is generalized to an extended linear empirical Bayes estimation technique which represents the Bayes estimator by a ...
Pensky, M., Ni, P.
core   +3 more sources

Bayesian Estimation of the Reliability Function of a Two-parameter Cauchy Distribution. [PDF]

open access: yesThe Egyptian Statistical Journal, 1998
            In this paper, we obtained an approximate Bayes procedure for the estimation of the reliability function of a two-parameter Cauchy distribution under a predictive distribution approach of Sinha and Guttman (1988) using Jeffrys' non ...
T. Abdel Moneim
doaj   +1 more source

On Bayes estimates

open access: yesJournal of Multivariate Analysis, 1973
AbstractIn this paper the author tries to give general conditions for the existence of Bayes estimates and for the consistency of sequences of Bayes estimates.In Section 3 we prove existence theorems for Bayes estimates, which contain those of DeGroot and Rao [3], as a special case.
openaire   +2 more sources

A Bayes Linear Bayes Method for Estimation of Correlated Event Rates [PDF]

open access: yesRisk Analysis, 2013
Typically, full Bayesian estimation of correlated event rates can be computationally challenging since estimators are intractable. When estimation of event rates represents one activity within a larger modeling process, there is an incentive to develop more efficient inference than provided by a full Bayesian model.
Quigley, John   +3 more
openaire   +4 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Bayes Shrinkage Estimation of the Parameter of Rayleigh Distribution for Progressive Type-II Censored Data

open access: yesAustrian Journal of Statistics, 2015
This paper derives Bayes shrinkage estimator of Rayleigh parameter and its associated risk based on conjugate prior under the assumption of general entropy loss function for progressive type-II censored data. Risk function of maximum likelihood estimate,
Sanku Dey   +2 more
doaj   +1 more source

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